This review summarizes the classification of tumors of the adrenal medulla and extra-
adrenal paraganglia as outlined in the 5th series of the WHO Classification of Endocrine and …

Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape
that allows their assignment to clusters based on underlying genetic alterations. With around …

Mitochondria are intracellular organelles involved in energy production, cell metabolism and
cell signaling. They are essential not only in the process of ATP synthesis, lipid metabolism …

Objective: The aim was to formulate clinical practice guidelines for pheochromocytoma and
paraganglioma (PPGL). Participants: The Task Force included a chair selected by the …

The classification working group of the International Society of Urological Pathology
consensus conference on renal neoplasia was in charge of making recommendations …

Paragangliomas and phaeochromocytomas are neuroendocrine tumours whose
pathogenesis and progression are very strongly influenced by genetics. A germline mutation …

Paragangliomas are neuroendocrine tumors frequently associated with mutations in RET,
NF1, VHL, and succinate dehydrogenase (SDHx) genes. Methylome analysis of a large …

Mutations in the human mitochondrial genome are known to cause an array of diverse
disorders, most of which are maternally inherited, and all of which are associated with …

Paragangliomas and pheochromocytomas (PPGL) are rare neuroendocrine tumours
characterized by a strong genetic determinism. Over the past 20 years, evolution of PPGL …

The succinate dehydrogenase (SDH) complex is a key respiratory enzyme composed of four
subunits: SDHA, SDHB, SDHC and SDHD. Remarkably, immunohistochemistry for SDHB …