Up to 50% of the people who have died from COVID-19 had metabolic and vascular
disorders. Notably, there are many direct links between COVID-19 and the metabolic and …

Post-traumatic stress disorder (PTSD) is a well-known mental illness, which is caused by
various stressors, including memories of past physical assaults and psychological pressure …

Background The majority of the critically ill patients may have critical illness-related
corticosteroid insufficiency (CIRCI). The therapeutic effect of dexamethasone may be related …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in
December 2019, causes coronavirus disease 2019 (COVID-19). It is reasonable to presume …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
the coronavirus 2019 (COVID-19) disease, which has caused a pandemic in 2020. This …

Chronic activation and dysregulation of the neuroendocrine stress response have severe
physiological and psychological consequences, including the development of metabolic and …

Chronic stress is a major cause of neuropsychiatric conditions such as depression. Stress
vulnerability varies individually in mice and humans, measured by behavioral changes. In …

Steroidogenic factor-1 (SF-1, also termed Ad4BP; NR5A1 in the official nomenclature) is a
nuclear receptor transcription factor that plays a crucial role in the regulation of adrenal and …

Background Increasing evidence suggests the role of gut microbiota in resilience versus
vulnerability after stress. However, the role of gut microbiota and microbiome-derived …

The adrenal gland is an essential component of the body stress response; it is formed by two
portions: a steroidogenic and a chromaffin tissue. Despite the anatomy of adrenal gland is …