Challenges of enzyme therapy: Why two players are better than one

S Cuoghi, R Caraffi, A Anderlini… - Wiley …, 2024 - Wiley Online Library
Enzyme‐based therapy has garnered significant attention for its current applications in
various diseases. Despite the notable advantages associated with the use of enzymes as …

Management of myocardial infarction complicated by cardiogenic shock: Expert opinion of the Association of Intensive Cardiac Care and Association of …

P Trzeciak, J Stępińska, R Gil… - Polish Heart …, 2023 - journals.viamedica.pl
Management of myocardial infarction complicated by cardiogenic shock: Expert opinion of the
Association of Intensive Cardiac C Page 1 www.journals.viamedica.pl/kardiologia_polska 1312 …

[HTML][HTML] Direct delivery of plasmin using clot-anchoring thrombin-responsive nanoparticles for targeted fibrinolytic therapy

M Sun, MHH Pontius, S Yang, T Pendekanti… - Journal of Thrombosis …, 2023 - Elsevier
Background Fibrin-rich clot formation in thrombo-occlusive pathologies is currently treated
by systemic administration of plasminogen activators (eg tPA), to convert fibrin-associated …

[HTML][HTML] Breaking the fibrinolytic speed limit with microwheel co‐delivery of tissue plasminogen activator and plasminogen

D Disharoon, BG Trewyn, PS Herson, DWM Marr… - Journal of Thrombosis …, 2022 - Elsevier
Background To reestablish blood flow in vessels occluded by clots, tissue plasminogen
activator (tPA) can be used; however, its efficacy is limited by transport to and into a clot and …

Advances in Functionalized Hydrogels in the Treatment of Myocardial Infarction and Drug-Delivery Strategies

Y Cao, R Fan, K Zhu, Y Gao - ACS Applied Materials & Interfaces, 2024 - ACS Publications
Myocardial infarction (MI) is a serious cardiovascular disease with high morbidity and
mortality rates, posing a significant threat to patient's health and quality of life. Following a …

[PDF][PDF] In silico design of new ketorolac bioisosteres as anti-inflammatory agents

CD Gamarra-Sánchez, CN Rodriguez-Silva… - J. Appl. Pharm …, 2024 - scholar.archive.org
Nonsteroidal anti-inflammatory drugs (NSAIDs) are over-the-counter drugs and one of the
most widely used pharmacological groups worldwide, their chronic use is limited due to their …

Propuesta de manejo inicial del infarto de miocardio con elevación del segmento ST no complicado en centros sin capacidad de intervención coronaria percutánea …

P Custodio-Sánchez, D Miranda-Noé… - Archivos peruanos de …, 2023 - scielo.org.pe
El infarto de miocardio con elevación del segmento ST (IMCEST) es una entidad clínica
cuyo tratamiento adecuado dependerá de su pronto reconocimiento, diagnóstico certero y …

[PDF][PDF] 常德农村地区急性ST 段抬高型心肌梗死患者院前溶栓治疗后的观察分析

姜辉, 杨柳, 郭杨, 向洁, 王阳光 - 临床急诊杂志, 2023 - lcjz.whuhzzs.com
目的: 探索常德农村地区急性ST 段抬高型心肌梗死(ST-segmentelevationmyocardialinfarction,
STEMI) 患者院前溶栓治疗后的临床结局和生存趋势. 方法: 观察2020-2022 …

[PDF][PDF] The effect of ticagrelor on myocardial microcirculation, cardiac function, and adverse cardiovascular events in STEMI patients after PCI.

DL Liu, WW Bao, XM Zeng, XT Liu… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: This study aimed to investigate the effects of ticagrelor on myocardial
microcirculation, cardiac function, and adverse cardiovascular events in ST-segment …

[PDF][PDF] Clinical value of GRACE score combined with DFR in predicting short-term prognosis of patients undergoing early PCI after thrombolysis for acute myocardial …

F Liu, XJ Liu, YP He, GB Liu, T Lan… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: The aim of the study was to investigate the clinical value of the Global Registry
of Arterial Events in Acute Coronary Syndromes (GRACE) score combined with the D …