[HTML][HTML] Polymeric nanoparticles in gene therapy: New avenues of design and optimization for delivery applications

R Rai, S Alwani, I Badea - Polymers, 2019 - mdpi.com
The field of polymeric nanoparticles is quickly expanding and playing a pivotal role in a wide
spectrum of areas ranging from electronics, photonics, conducting materials, and sensors to …

Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years

N Kapate, JR Clegg, S Mitragotri - Advanced Drug Delivery Reviews, 2021 - Elsevier
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

E Ben-Akiva, RA Meyer, H Yu, JT Smith, DM Pardoll… - Science …, 2020 - science.org
The design of next-generation nanobiomaterials requires precise engineering of both
physical properties of the core material and chemical properties of the material's surface to …

Microparticles in contact with cells: from carriers to multifunctional tissue modulators

MD Neto, MB Oliveira, JF Mano - Trends in biotechnology, 2019 - cell.com
For several decades microparticles have been exclusively and extensively explored as
spherical drug delivery vehicles and large-scale cell expansion carriers. More recently …

Effects of the microparticle shape on cellular uptake

Y He, K Park - Molecular pharmaceutics, 2016 - ACS Publications
Physical forms of microparticles and nanoparticles, such as the size, charge, and shape, are
known to affect endocytosis. Improving the physical designs of the drug carriers can …

Biomimetic particles as therapeutics

RA Meyer, JC Sunshine, JJ Green - Trends in biotechnology, 2015 - cell.com
In recent years, there have been major advances in the development of novel nanoparticle-
and microparticle-based therapeutics. An emerging paradigm is the incorporation of …

Shape matters: Biodegradable anisotropic nanoparticle artificial antigen presenting cells for cancer immunotherapy

E Ben-Akiva, JW Hickey, RA Meyer, A Isser… - Acta biomaterialia, 2023 - Elsevier
Artificial antigen presenting cells are biomimetic particles that recapitulate the signals
presented by natural antigen presenting cells in order to stimulate T cells in an antigen …

Entanglement-based thermoplastic shape memory polymeric particles with photothermal actuation for biomedical applications

Q Guo, CJ Bishop, RA Meyer, DR Wilson… - … applied materials & …, 2018 - ACS Publications
Triggering shape-memory functionality under clinical hyperthermia temperatures could
enable the control and actuation of shape-memory systems in clinical practice. For this …

[HTML][HTML] Development of PLGA micro-and nanorods with high capacity of surface ligand conjugation for enhanced targeted delivery

J Cao, JS Choi, MA Oshi, J Lee, N Hasan, J Kim… - Asian Journal of …, 2019 - Elsevier
Particle shape has been recognized as one of the key properties of nanoparticles in
biomedical applications including targeted drug delivery. Targeting ability of shape …

Biomimetic and bioinspired nanoparticles for targeted drug delivery

M Gagliardi - Therapeutic delivery, 2017 - Taylor & Francis
In drug targeting, the urgent need for more effective and less iatrogenic therapies is pushing
toward a complete revision of carrier setup. After the era of 'articles used as homing …