Bacterial infections remain a significant threat to the health of newborns and adults. Group B
Streptococci (GBS) are Gram-positive bacteria that are common asymptomatic colonizers of …

Given the constant synthesis and degradation of hyaluronan (hyaluronic acid, HA) in tissues,
it is remarkable that the human body maintains precise levels of hyaluronan as tightly as it …

An enzyme hyaluronidase (hyase) producing halotolerant bacterium was isolated from
dental caries and identified as Brevibacterium halotolerans DC1. Higher growth and hyase …

Streptococcus equi is the causative agent of the highly contagious disease" strangles" in
equines and zoonotic meningitis in human. Spreading of infection in host tissues is thought …

Streptococcus pyogenes is associated with a wide variety of mucosal and invasive infections
that claim human life. The conversion from non pathogenic to toxigenic strain of S. pyogenes …

Hyaluronate lyase cleaves hyaluronan chains at a β-d-GalNAc-(1→ 4)-β-d-GlcA bond,
ultimately breaking the polysaccharide down to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl …

Hyaluronate (HA) lyase of Streptococcus pyogenes bacteriophage H4489A, was expressed
in Escherichia coli, purified, and characterized. The purified homogeneous preparation of …

Hyaluronate lyase from Spectrococcus pneumonia can degrade hyaluronic acid, which is
one of the major components in the extracellular matrix. The major functions of hyaluronan …

Background α-isopropylmalate synthase (MtαIPMS), an enzyme that catalyzes the first
committed step of the leucine biosynthetic pathway of Mycobacterium tuberculosis is a …

Gly-XY (Gly represents glycine) motif is a collagen-like repeat present at the N-terminal
domain of bacteriophage hyaluronate lyase (Phage HL). It addition in providing …