Lytic Cycle of Toxoplasma gondii: 15 Years Later

IJ Blader, BI Coleman, CT Chen… - Annual review of …, 2015 - annualreviews.org
Toxoplasmosis is the clinical and pathological consequence of acute infection with the
obligate intracellular apicomplexan parasite Toxoplasma gondii. Symptoms result from …

Overview of Poultry Eimeria Life Cycle and Host-Parasite Interactions

S López-Osorio, JJ Chaparro-Gutiérrez… - Frontiers in Veterinary …, 2020 - frontiersin.org
Apicomplexan parasites of the genus Eimeria are organisms which invade the intestinal
tract, causing coccidiosis, an enteric disease of major economic importance worldwide. The …

Strain-specific activation of the NF-κB pathway by GRA15, a novel Toxoplasma gondii dense granule protein

EE Rosowski, D Lu, L Julien, L Rodda… - Journal of Experimental …, 2011 - rupress.org
NF-κB is an integral component of the immune response to Toxoplasma gondii. Although
evidence exists that T. gondii can directly modulate the NF-κB pathway, the parasite-derived …

Kiss and spit: the dual roles of Toxoplasma rhoptries

JC Boothroyd, JF Dubremetz - Nature Reviews Microbiology, 2008 - nature.com
Toxoplasma gondii is a single-celled, eukaryotic parasite that can only reproduce inside a
host cell. Upon entry, this Apicomplexan parasite co-opts host functions for its own purposes …

The immunobiology of the innate response to Toxoplasma gondii

CM Miller, NR Boulter, RJ Ikin, NC Smith - International journal for …, 2009 - Elsevier
Toxoplasma gondii is a unique intracellular parasite. It can infect a variety of cells in virtually
all warm-blooded animals. It has a worldwide distribution and, overall, around one-third of …

Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence

IJ Blader, JP Saeij - Apmis, 2009 - Wiley Online Library
Toxoplasma gondii is an obligate intracellular protozoan parasite that can infect most warm‐
blooded animals and cause severe and life‐threatening disease in developing fetuses and …

Modulation of tumor necrosis factor by microbial pathogens

MM Rahman, G McFadden - PLoS pathogens, 2006 - journals.plos.org
In response to invasion by microbial pathogens, host defense mechanisms get activated by
both the innate and adaptive arms of the immune responses. TNF (tumor necrosis factor) is a …

Host cell manipulation by the human pathogen Toxoplasma gondii

J Laliberte, VB Carruthers - Cellular and molecular life sciences, 2008 - Springer
Toxoplasma gondii is an obligate intracellular parasite that can infect virtually any nucleated
cell. During invasion Toxoplasma creates the parasitophorous vacuole, a subcellular …

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

YO Zhao, A Khaminets, JP Hunn, JC Howard - PLoS pathogens, 2009 - journals.plos.org
Toxoplasma gondii is a natural intracellular protozoal pathogen of mice and other small
mammals. After infection, the parasite replicates freely in many cell types (tachyzoite stage) …

NF-κB translocation prevents host cell death after low-dose challenge by Legionella pneumophila

VP Losick, RR Isberg - The Journal of experimental medicine, 2006 - rupress.org
Legionella pneumophila, the causative agent of Legionnaires' disease, grows within
macrophages and manipulates target cell signaling. Formation of a Legionella-containing …