[HTML][HTML] Inhibitory control of the excitatory/inhibitory balance in psychiatric disorders
Neuronal networks consist of different types of neurons that all play their own role in order to
maintain proper network function. The two main types of neurons segregate in excitatory and …
maintain proper network function. The two main types of neurons segregate in excitatory and …
Moving towards causality in attention-deficit hyperactivity disorder: overview of neural and genetic mechanisms
EF Gallo, J Posner - The Lancet Psychiatry, 2016 - thelancet.com
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder
characterised by developmentally inappropriate levels of inattention and hyperactivity or …
characterised by developmentally inappropriate levels of inattention and hyperactivity or …
The Correlation of the Neuronal Long‐Range Temporal Correlations, Avalanche Dynamics with the Behavioral Scaling Laws and Interindividual Variability
Spontaneous infra‐slow fluctuations (ISFs) in both neuronal firing rates and membrane
potentials are a defining characteristic of fast (< 1 Hz) mammalian brain activity both in vitro …
potentials are a defining characteristic of fast (< 1 Hz) mammalian brain activity both in vitro …
[HTML][HTML] Long noncoding RNAs with snoRNA ends
We describe the discovery of sno-lncRNAs, a class of nuclear-enriched intron-derived long
noncoding RNAs (lncRNAs) that are processed on both ends by the snoRNA machinery …
noncoding RNAs (lncRNAs) that are processed on both ends by the snoRNA machinery …
[HTML][HTML] Neuron-glia interactions in neurodevelopmental disorders
YS Kim, J Choi, BE Yoon - Cells, 2020 - mdpi.com
Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …
diseases, and that glial cells participate in synapse formation, development, and plasticity …
Norepinephrine versus dopamine and their interaction in modulating synaptic function in the prefrontal cortex
Among the neuromodulators that regulate prefrontal cortical circuit function, the
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …
Linking microcircuit dysfunction to cognitive impairment: effects of disinhibition associated with schizophrenia in a cortical working memory model
Excitation–inhibition balance (E/I balance) is a fundamental property of cortical
microcircuitry. Disruption of E/I balance in prefrontal cortex is hypothesized to underlie …
microcircuitry. Disruption of E/I balance in prefrontal cortex is hypothesized to underlie …
Thalamic reticular impairment underlies attention deficit in Ptchd1Y/− mice
Developmental disabilities, including attention-deficit hyperactivity disorder (ADHD),
intellectual disability (ID), and autism spectrum disorders (ASD), affect one in six children in …
intellectual disability (ID), and autism spectrum disorders (ASD), affect one in six children in …
[HTML][HTML] Molecular mechanisms of presynaptic membrane retrieval and synaptic vesicle reformation
NL Kononenko, V Haucke - Neuron, 2015 - cell.com
The function of the nervous system depends on the exocytotic release of neurotransmitter
from synaptic vesicles (SVs). To sustain neurotransmission, SV membranes need to be …
from synaptic vesicles (SVs). To sustain neurotransmission, SV membranes need to be …
The molecular genetic architecture of attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder (ADHD) is a common childhood behavioral condition
which affects 2–10% of school age children worldwide. Although the underlying molecular …
which affects 2–10% of school age children worldwide. Although the underlying molecular …