Signaling pathways in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma

K Maslenkina, L Mikhaleva, M Naumenko… - International Journal of …, 2023 - mdpi.com
Barrett's esophagus (BE) is a premalignant lesion that can develop into esophageal
adenocarcinoma (EAC). The development of Barrett's esophagus is caused by biliary reflux …

Abnormal upregulation of NUBP2 contributes to cancer progression in colorectal cancer

D Lan, J Wang, G Sun, L Jiang, Q Chen, S Li… - Molecular and Cellular …, 2024 - Springer
Colorectal cancer (CRC), a digestive tract malignancy with high mortality and morbidity,
lacks effective biomarkers for clinical prognosis due to its complex molecular pathogenesis …

Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma

Z Gu, C Shi, J Li, Y Han, B Sun, W Zhang, J Wu, G Zhou… - BMC medicine, 2022 - Springer
Background Deregulation of cell-cycle pathway is ubiquitously observed in human
papillomavirus negative (HPVneg) head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] The immune underpinnings of Barrett's-associated adenocarcinogenesis: a retrial of nefarious immunologic co-conspirators

L Tambunting, D Kelleher, SP Duggan - Cellular and Molecular …, 2022 - Elsevier
There is no doubt that chronic gastroesophageal reflux disease increases the risk of
esophageal adenocarcinoma (EAC) by several fold (odds ratio, 6.4; 95% CI, 4.6–9.1), and …

Mystery Solving: Acid Reflux and Cell Mobility in Barrett's Esophagus and Esophageal Adenocarcinoma

F Mckeon, W Xian - Cellular and Molecular Gastroenterology and …, 2020 - cmghjournal.org
Gastroesophageal reflux disease is remarkably common and usually benign, and yet it is a
risk factor for Barrett's esophagus (BE), the precursor of potentially lethal esophageal …