Pyroptosis: mechanisms and diseases

P Yu, X Zhang, N Liu, L Tang, C Peng… - Signal transduction and …, 2021 - nature.com
Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

[HTML][HTML] Molecular mechanisms of viral hepatitis induced hepatocellular carcinoma

S D'souza, KCK Lau, CS Coffin… - World journal of …, 2020 - ncbi.nlm.nih.gov
Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead
to cirrhosis, cancer, and liver failure. Liver cancer is the third leading cause of cancer …

Geographical similarity and differences in the burden and genetic predisposition of NAFLD

TCF Yip, E Vilar‐Gomez, S Petta, Y Yilmaz… - Hepatology, 2023 - journals.lww.com
NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …

Global epidemiology and burden of HCV infection and HCV-related disease

AP Thrift, HB El-Serag, F Kanwal - Nature reviews Gastroenterology & …, 2017 - nature.com
Chronic HCV infection is a global health problem that affects> 184 million people worldwide.
HCV is associated with several hepatic and extrahepatic disorders, including several …

NAFLD, NASH and liver cancer

GA Michelotti, MV Machado, AM Diehl - … reviews Gastroenterology & …, 2013 - nature.com
NAFLD affects a large proportion of the US population and its incidence and prevalence are
increasing to epidemic proportions around the world. As with other liver diseases that cause …

[HTML][HTML] Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace

G Baffy, EM Brunt, SH Caldwell - Journal of hepatology, 2012 - Elsevier
Hepatocellular carcinoma (HCC) is a common cancer worldwide that primarily develops in
cirrhosis resulting from chronic infection by hepatitis B virus and hepatitis C virus, alcoholic …

Pathological features of fatty liver disease

MM Yeh, EM Brunt - Gastroenterology, 2014 - Elsevier
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are significant
causes of chronic liver disease worldwide. Both are characterized by histological lesions …

The epidemiology of nonalcoholic fatty liver disease: a global perspective

M Lazo, JM Clark - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized cause of liver
disease in the United States and worldwide. With obesity being an important risk factor …

Lipid metabolism in development and progression of hepatocellular carcinoma

M Sangineto, R Villani, F Cavallone, A Romano… - Cancers, 2020 - mdpi.com
Metabolic reprogramming is critically involved in the development and progression of
cancer. In particular, lipid metabolism has been investigated as a source of energy, micro …

Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease

AS Lok, LB Seeff, TR Morgan, AM Di Bisceglie… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Although the incidence of hepatocellular carcinoma (HCC) is
increasing in the United States, data from large prospective studies are limited. We …