Emerging predictive biomarkers for novel therapeutics in peripheral T-cell and natural killer/T-cell lymphoma

DRY Yap, JQ Lim, D Huang, CK Ong… - Frontiers in …, 2023 - frontiersin.org
Peripheral T-cell lymphoma (PTCL) and natural killer/T-cell lymphoma (NKTCL) are rare
subtypes of non-Hodgkin's lymphoma that are typically associated with poor treatment …

Prognostic significance of the neutrophil-to-lymphocyte ratio in peripheral T-cell lymphoma: a meta-analysis

J Liu, S Zhang, R Mi, L Chen, Q Yin - Cancer Cell International, 2021 - Springer
The neutrophil-to-lymphocyte ratio (NLR) as an inflammatory marker may represent changes
between inflammation and host immunity that affect the prognosis of peripheral T-cell …

How to identify patients at high risk of developing nasal-type, extranodal nature killer/T-cell lymphoma-associated hemophagocytic syndrome

N Li, M Jiang, WC Wu, WW Wei, LQ Zou - Frontiers in oncology, 2021 - frontiersin.org
Nasal-type, extranodal nature killer (NK)/T-cell lymphoma-associated hemophagocytic
syndrome (NK/T-LAHS) is a rare and life-threatening disease, requiring investigation of risk …

Prognostic role of blood markers in primary central nervous system lymphoma patients treated with high-dose methotrexate-based therapy

Q Luo, C Yang, C Fu, W Wu, Y Wei, L Zou - Frontiers in Oncology, 2021 - frontiersin.org
Purpose: Primary central nervous system lymphoma (PCNSL) is a rare type of extra-nodal
non-Hodgkin lymphoma, but the prognostic value of blood parameters indicating systemic …

Clinical features and survival outcomes of ocular melanoma in a multi-ethnic Asian cohort

LLY Tan, J Hong, WL Goh, EWY Chang, VS Yang… - Scientific reports, 2020 - nature.com
Ocular melanomas are uncommon cancers in Southeast Asia unlike in the West. We
conducted a retrospective review of patients (n= 44) with histologically-proven ocular …

A novel prognostic index for extranodal natural killer/T-cell lymphoma in the era of pegaspargase/L-asparaginase

Z Shen, X Zhang, Y Li, X Chen, X Xing, H Zhang… - Future …, 2024 - Taylor & Francis
Aim: This multicenter retrospective study aimed to develop a novel prognostic system for
extranodal natural killer/T-cell lymphoma (ENKTL) patients in the era of pegaspargase/L …

Novel clinical risk stratification and treatment strategies in relapsed/refractory peripheral T-cell lymphoma

EWY Chang, YH Tan, JY Chan - Journal of Hematology & Oncology, 2024 - Springer
Peripheral T cell lymphoma (PTCL) represents a group of heterogeneous hematological
malignancies, which are notoriously challenging to treat and outcomes are typically poor …

Extranodal lymphoma: pathogenesis, diagnosis and treatment

H Yang, Y Xun, C Ke, K Tateishi, H You - Molecular Biomedicine, 2023 - Springer
Approximately 30% of lymphomas occur outside the lymph nodes, spleen, or bone marrow,
and the incidence of extranodal lymphoma has been rising in the past decade. While …

Clinical implications of systemic and local immune responses in human angiosarcoma

JY Chan, GF Tan, J Yeong, CW Ong, DYX Ng… - NPJ Precision …, 2021 - nature.com
Angiosarcomas are a rare subtype of soft-tissue sarcomas which exhibit aggressive clinical
phenotypes with limited treatment options and poor outcomes. In this study, we investigated …

Comparative analysis of clinicopathologic characteristics and prognosis between nasal and nonnasal extranodal NK/T‐cell lymphoma

Z Shen, X Chen, C Sun, T Lu, Y Shi, H Zhang… - Cancer …, 2023 - Wiley Online Library
Background The clinicopathologic characteristics and prognosis of nasal and nonnasal
extranodal natural killer T‐cell lymphoma (ENKTL) are considered to be different. However …