The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …

The study of corneal stromal keratocytes is motivated by its strong association with corneal
health and visual function. They play a dominant role in the maintenance of corneal …

Recent advances in the field of ophthalmology show great potential in the design of
bioengineered constructs to mimic the corneal stroma. Hydrogels based on synthetic …

Corneal blindness due to scarring is conventionally treated by corneal transplantation, but
the shortage of donor materials has been a major issue affecting the global success of …

The cornea is a highly innervated tissue, exhibiting a complex nerve architecture,
distribution, and structural organization. Significant contributions over the years have …

The loss of ocular surface (OS) homeostasis characterizes the onset of dry eye disease.
Resilience defines the ability to withstand this threat, reflecting the ability of the ocular …

The cornea is a valuable tissue for studying peripheral sensory nerve structure and
regeneration due to its avascularity, transparency, and dense innervation. Somatosensory …

Purpose: Obesity is associated with peripheral neuropathy, which bariatric surgery may
ameliorate. The aim of this study was to assess whether corneal confocal microscopy can …

Abnormal nerve regeneration often follows corneal injury, predisposing patients to pain, dry
eye and vision loss. Yet, we lack a mechanistic understanding of this process. A key event in …

Purpose: To evaluate the safety and feasibility of intrastromal injection of human corneal
stromal keratocytes (CSKs) and its therapeutic effect on a rodent early corneal opacity …