Chronic ethanol exposure induces deleterious changes in cardiomyocytes derived from human induced pluripotent stem cells
Chronic alcohol consumption in adults can induce cardiomyopathy, arrhythmias, and heart
failure. In newborns, prenatal alcohol exposure can increase the risk of congenital heart …
failure. In newborns, prenatal alcohol exposure can increase the risk of congenital heart …
Using zebrafish to analyze the genetic and environmental etiologies of congenital heart defects
R Shrestha, J Lieberth, S Tillman, J Natalizio… - Animal Models of …, 2020 - Springer
Congenital heart defects (CHDs) are among the most common human birth defects.
However, the etiology of a large proportion of CHDs remains undefined. Studies identifying …
However, the etiology of a large proportion of CHDs remains undefined. Studies identifying …
Folic acid reduces the ethanol-induced morphological and behavioral defects in embryonic and larval zebrafish (Danio rerio) as a model for fetal alcohol spectrum …
The objective of this work was to determine whether folic acid (FA) reduces the embryonic
ethanol (EtOH) exposure induced behavioral and morphological defects in our zebrafish …
ethanol (EtOH) exposure induced behavioral and morphological defects in our zebrafish …
Chronic ethanol exposure induces mitochondrial dysfunction and alters gene expression and metabolism in human cardiac spheroids
Background Chronic alcohol consumption in adults can induce various cardiac toxicities
such as arrhythmias, cardiomyopathy, and heart failure. Prenatal alcohol exposure can …
such as arrhythmias, cardiomyopathy, and heart failure. Prenatal alcohol exposure can …
Evaluation of developmental toxicity in zebrafish embryos and antiproliferative potential against human tumor cell lines of new derivatives containing 4-nitrophenyl …
A Szopa, M Herbet, A Pachuta-Stec… - Toxicology and Applied …, 2023 - Elsevier
The aim of the studies was to evaluate the antiproliferative potential against human tumor
cell lines of newly synthetized derivatives containing 4-nitrophenyl group, as well as its …
cell lines of newly synthetized derivatives containing 4-nitrophenyl group, as well as its …
Embryonic ethanol exposure alters expression of sox2 and other early transcripts in zebrafish, producing gastrulation defects
Ethanol exposure during prenatal development causes fetal alcohol spectrum disorder
(FASD), the most frequent preventable birth defect and neurodevelopmental disability …
(FASD), the most frequent preventable birth defect and neurodevelopmental disability …
Protective effects of quercetin, polydatin, and folic acid and their mixtures in a zebrafish (Danio rerio) fetal alcohol spectrum disorder model
Protective effects of quercetin (QUE), polydatin (POL), and folic acid (FA) and their mixtures
were tested using zebrafish to model fetal alcohol spectrum disorder in this study. Zebrafish …
were tested using zebrafish to model fetal alcohol spectrum disorder in this study. Zebrafish …
Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation
DC Harvey, P De Zoysa, O Toubat, J Choi… - Birth defects …, 2022 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) is associated with an increased incidence of
congenital heart defects (CHD), in particular outflow tract (OFT) defects. However, the …
congenital heart defects (CHD), in particular outflow tract (OFT) defects. However, the …
Newly synthesized derivatives with a thiosemicarbazide group reduce the viability of cancer cell lines. Acute toxicity assessment in Zebrafish (Danio rerio) early life …
ŁJ Walczak-Nowicka, A Szopa, M Pitucha, A Serefko… - Toxicology in Vitro, 2024 - Elsevier
Due to the variability and ability of tumor to mutate, as well as the heterogeneity of tumor
tissue, such drugs are sought that would act selectively and multidirectionally on the cancer …
tissue, such drugs are sought that would act selectively and multidirectionally on the cancer …
Embryonic alcohol exposure in zebrafish predisposes adults to cardiomyopathy and diastolic dysfunction
Aims Fetal alcohol spectrum disorders (FASDs) impact up to 0.8% of the global population.
However, cardiovascular health outcomes in adult patients, along with predictive biomarkers …
However, cardiovascular health outcomes in adult patients, along with predictive biomarkers …