Background A very large biomass of intact asexual-stage malaria parasites accumulates in
the spleen of asymptomatic human individuals infected with Plasmodium vivax. The …

Malaria, caused by parasites of the Plasmodium species and transmitted through the bites of
infected female Anopheles mosquitoes, is still a fatal and dangerous disease in mainly …

Metabolites are critical products and mediators of cellular and tissue function, and key
signals in cell-to-cell, organ-to-organ and cross-organism communication. Many of these …

Background Malaria-associated anaemia, arising from symptomatic, asymptomatic and
submicroscopic infections, is a significant cause of morbidity worldwide. Induced blood …

This article is inter alia a brief, first-stop guide to possible adverse events (AEs) associated
with tafenoquine (TQ) intake. Safety and efficacy findings for TQ in Plasmodium vivax …

Cerebral malaria is the most serious manifestation of severe falciparum malaria.
Sequestration of infected red blood cells and microvascular dysfunction are key contributing …

The rapid emergence and spread of antimalarial resistance, especially artemisinin
resistance in Plasmodium falciparum, has led to the use of volunteer infection studies (VIS) …

Plasmodium falciparumis not only the most predominant human malaria parasite species in
Africa but is additionally responsible for causing the most severe cases of the disease. This …

Plasmodium vivax contributes significantly to global malaria morbidity. Key advances
include the discovery of pathways facilitating invasion by P. vivax merozoites of nascent …