Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

Resistance development to bacteriophages occurring during bacteriophage therapy

F Oechslin - Viruses, 2018 - mdpi.com
Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …

Unlocking the next generation of phage therapy: the key is in the receptors

FLG Altamirano, JJ Barr - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Phages need to attach to a receptor on the bacterial surface to initiate infection.•It
is not common practice to identify these receptors before phage therapy use.•Identifying …

Bacteriophage-host arm race: an update on the mechanism of phage resistance in bacteria and revenge of the phage with the perspective for phage therapy

AH Azam, Y Tanji - Applied microbiology and biotechnology, 2019 - Springer
Due to a constant attack by phage, bacteria in the environment have evolved diverse
mechanisms to defend themselves. Several reviews on phage resistance mechanisms have …

[HTML][HTML] A combination therapy of Phages and Antibiotics: Two is better than one

X Li, Y He, Z Wang, J Wei, T Hu, J Si… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Emergence of antibiotic resistance presents a major setback to global health, and shortage
of antibiotic pipelines has created an urgent need for development of alternative therapeutic …

Non‐antibiotic approaches to combat motile Aeromonas infections in aquaculture: Current state of knowledge and future perspectives

LT Dien, TPH Ngo, TV Nguyen… - Reviews in …, 2023 - Wiley Online Library
Inland aquaculture contributed by three major fish groups, including carps, tilapias, and
catfish plays a vital role in global food security and nutrition, particularly in low and middle …

High-throughput mapping of the phage resistance landscape in E. coli

VK Mutalik, BA Adler, HS Rishi, D Piya, C Zhong… - PLoS …, 2020 - journals.plos.org
Bacteriophages (phages) are critical players in the dynamics and function of microbial
communities and drive processes as diverse as global biogeochemical cycles and human …

Phages and their potential to modulate the microbiome and immunity

S Federici, SP Nobs, E Elinav - Cellular & molecular immunology, 2021 - nature.com
Bacteriophages (hence termed phages) are viruses that target bacteria and have long been
considered as potential future treatments against antibiotic-resistant bacterial infection …

Virulence reduction in bacteriophage resistant bacteria

M León, R Bastías - Frontiers in microbiology, 2015 - frontiersin.org
Bacteriophages can influence the abundance, diversity, and evolution of bacterial
communities. Several bacteriophages have been reported to add virulence factors to their …

Overcoming the challenges of phage therapy for industrial aquaculture: A review

A Culot, N Grosset, M Gautier - Aquaculture, 2019 - Elsevier
Aquaculture is the fastest-growing sector in food industry. Its development is powered by the
intensification of the production which increased bacterial disease occurrence and …