The mammary gland is one of the most regenerative organs in the body, with the majority of
development occurring postnatally and in the adult mammal. Formation of the ductal tree is …

Pancreatic cancer (PaCa) has the highest death rate and incidence is increasing. Poor
prognosis is due to late diagnosis and early metastatic spread, which is ascribed to a minor …

Snail1, a key transcription factor of epithelial–mesenchymal transition (EMT), is subjected to
ubiquitination and degradation, but the mechanism by which Snail1 is stabilized in tumours …

CD151 is a transmembrane protein implicated in tumor progression and has been shown to
regulate various cellular and molecular mechanisms contributing to malignancy. More …

Glioblastoma, one of the most aggressive forms of brain cancer, is featured by high tumor
cell motility and invasiveness, which not only fuel tumor infiltration, but also enable escape …

The mammary gland is dynamically remodelled during its postnatal development and the
reproductive cycles. This inherent plasticity has been suggested to increase the …

Simple Summary Tetraspanins are a family of molecules abundantly expressed on the
surface of normal or tumor cells. They have been implicated in recruiting or sequestering key …

Triple-negative breast cancer is high heterogeneous, aggressive, and metastatic with poor
prognosis. Despite of advances in targeted therapies, TNBC has been reported to cause …

Glioblastoma (GBM) stem cells (GSCs) represent tumor-propagating cells with stem-like
characteristics (stemness) that contribute disproportionately to GBM drug resistance and …

Successful lactation and the risk for developing breast cancer depend on growth and
differentiation of the mammary gland (MG) epithelium that is regulated by ovarian steroids …