Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Increasing evidence indicates that the tumor microenvironment has critical roles in all
aspects of cancer biology, including growth, angiogenesis, metastasis and progression …

Simple Summary In cancer, disseminated neoplastic cells circulating in blood are a source
of tumor DNA, RNA, and protein, which can be harnessed to diagnose, monitor, and better …

Background: Dupuytren disease is a fibroproliferative disease of palmar fascia of the hand.
Its prevalence has been the subject of several reviews; however, an accurate description of …

Although molecular mechanisms driving tumor progression have been extensively studied,
the biological nature of the various populations of circulating tumor cells (CTCs) within the …

Circulating tumor cells (CTCs) are the potential precursors of metastatic disease. Most
assays established for the enumeration of CTCs so far–including the gold standard …

Simple Summary Even though it is known that (cancer) cells can fuse, it is still less
understood how (cancer) cells merge their plasma membranes, thereby giving rise to bi-and …

Introduction Various subtypes of circulating cancer-associated cells in the blood are
described. A unique circulating, large, and polymorphonuclear cell with a dual epithelial and …

Cellular fusion eg between cancer cells and normal cells represents a stepwise process that
is tightly regulated. During a pre-hybrid preparation program somatic cells and/or cancer …

Tumor cells actively contribute to constructing their own microenvironment during
tumorigenesis and tumor progression. The tumor microenvironment contains multiple types …