Designing spatial and temporal control of vaccine responses

GA Roth, VCTM Picece, BS Ou, W Luo… - Nature Reviews …, 2022 - nature.com
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Nanovaccine: An emerging strategy

A Das, N Ali - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Vaccination is so far the most effective way of eradicating infections. Rapidly
emerging drug resistance against infectious diseases and chemotherapy-related toxicities in …

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

Mannose in vaccine delivery

UJ Nahar, I Toth, M Skwarczynski - Journal of Controlled Release, 2022 - Elsevier
Adjuvants and vaccine delivery systems are used widely to improve the efficacy of vaccines.
Their primary roles are to protect antigen from degradation and allow its delivery and uptake …

Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice

JL Mangal, S Inamdar, T Le, X Shi, M Curtis, H Gu… - Biomaterials, 2021 - Elsevier
Dendritic cells (DCs) rely on glycolysis for their energy needs to induce pro-inflammatory
antigen-specific immune responses. Therefore, inhibiting DC glycolysis, while presenting …

Metal–organic coordination polymer for delivery of a subunit broadly acting influenza vaccine

M Eckshtain-Levi, CJ Batty, LM Lifshits… - … applied materials & …, 2022 - ACS Publications
A zinc-carnosine (ZnCar) metal–organic coordination polymer was fabricated in biologically
relevant N-(2-hydroxyethyl) piperazine-N′-ethanesulfonic acid (HEPES) buffer for use as a …

Micro and nanotechnologies: The little formulations that could

RT Stiepel, E Duggan, CJ Batty… - … & Translational Medicine, 2023 - Wiley Online Library
The first publication of micro‐and nanotechnology in medicine was in 1798 with the use of
the Cowpox virus by Edward Jenner as an attenuated vaccine against Smallpox. Since then …

Metal–organic coordination polymers for delivery of immunomodulatory agents, and infectious disease and cancer vaccines

ES Pena, LM Lifshits, M Eckshtain‐Levi… - Wiley …, 2023 - Wiley Online Library
Metal–organic coordination polymers (CPs) are a broad class of materials that include metal–
organic frameworks (MOFs). CPs are highly ordered crystalline materials that are composed …