Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

Objective: Disrupted emotional processing is a common feature of many psychiatric
disorders. The authors investigated functional disruptions in neural circuitry underlying …

The mediodorsal nucleus of the thalamus (MD) has been implicated in executive functions
(such as planning, cognitive control, working memory, and decision-making) because of its …

The limbic system is a phylogenetically old, behaviorally defined system that serves as a
center for emotions. It controls the expression of anger, fear, and joy and also influences …

The ability to adapt to dynamic environments requires tracking multiple signals with variable
sensory salience and fluctuating behavioral relevance. This complex process requires …

Basolateral amygdala (BLA) projects widely across the macaque frontal cortex, and
amygdalo-frontal projections are critical for appropriate emotional responding and decision …

Background Social discrimination, a type of psychological stressor, is associated with poorer
physical and mental health outcomes, yet we have little understanding of how discrimination …

Previous MRI studies confirmed abnormalities in the limbic-cortical-striatal-pallidal-thalamic
(LCSPT) network or limbic-cortico-striatal-thalamic-cortical (LCSTC) circuits in patients with …

The mediodorsal thalamus (MD) and anterior thalamic nuclei (ATN) are two adjacent brain
nodes that support our ability to make decisions, learn, update information, form and retrieve …