Reviewing the variability in urinary concentrations of non-persistent organic chemicals: evaluation across classes, sampling strategies and dilution corrections

M Roggeman, C Gys, A Klimowska, M Bastiaensen… - Environmental …, 2022 - Elsevier
Various biomonitoring studies have been carried out to investigate the exposure of
populations by measuring non-persistent organic chemicals in urine. To accurately assess …

[HTML][HTML] A review of in silico toxicology approaches to support the safety assessment of cosmetics-related materials

MTD Cronin, SJ Enoch, JC Madden, JF Rathman… - Computational …, 2022 - Elsevier
In silico tools and resources are now used commonly in toxicology and to support the “Next
Generation Risk Assessment”(NGRA) of cosmetics ingredients or materials. This review …

[HTML][HTML] Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materials

AM Api, D Basketter, J Bridges, P Cadby, G Ellis… - Regulatory Toxicology …, 2020 - Elsevier
In 2008, a proposal for assessing the risk of induction of skin sensitization to fragrance
materials Quantitative Risk Assessment 1 (QRA1) was published. This was implemented for …

Amended safety assessment of parabens as used in cosmetics

P Cherian, J Zhu, WF Bergfeld… - … journal of toxicology, 2020 - journals.sagepub.com
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 21 parabens
as preservatives in cosmetic products. All of these ingredients are reported to function in …

Assessing human exposure to chemicals in materials, products and articles: the international risk management landscape for phthalates

CMA Eichler, EA Cohen Hubal… - Environmental science & …, 2019 - ACS Publications
Risk-based chemical safety assessments are increasingly being conducted to support
chemical management decisions and informed substitution to protect public health. Rapid …

Exposure assessment

DJ Paustenbach, AK Madl… - Human and Ecological …, 2024 - Wiley Online Library
Exposure assessment describes the nature, magnitude, duration, and extent to which
various populations are exposed to a chemical agent and is a critical step in the risk …

Is it realistic to propose determination of a lifetime internal exposome?

G Sabbioni, JD Berset, BW Day - Chemical Research in …, 2020 - ACS Publications
Biomonitoring of xenobiotics has been performed for many years in occupational and
environmental medicine. It has revealed hidden exposures and the exposure of workers …

Roadmap for action for advancing aggregate exposure to chemicals in the EU

L Lamon, J Doyle, A Paini, R Moeller… - EFSA Supporting …, 2024 - Wiley Online Library
Abstract The European Food Safety Authority (EFSA) has a goal to efficiently conduct
aggregate exposure assessments (AEAs) for chemicals using both exposure models and …

Aggregate exposure assessment using cosmetic co-use scenarios: II. Application and validation for phthalates

M Lim, K Lee - Food and Chemical Toxicology, 2020 - Elsevier
Aggregate exposure assessments using co-use scenarios could provide more realistic
estimations than single product exposure assessment. Co-use scenarios for cosmetic …

Aggregate exposure assessment using cosmetic co-use scenarios: I. Establishment of aggregate exposure scenarios

M Lim, K Lee - Food and Chemical Toxicology, 2020 - Elsevier
The “co-use” patterns of cosmetics would be critical for accurate aggregate exposure
assessment. The Korean national representative exposure factor database, which includes …