A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

The chicken continues to hold its position as a leading model organism within many areas of
research, as well as being a major source of protein for human consumption. The First …

Next generation sequencing has made it possible to perform differential gene expression
studies in non-model organisms. For these studies, the need for a reference genome is …

Y chromosomes underlie sex determination in mammals, but their repeat-rich nature has
hampered sequencing and associated evolutionary studies. Here we trace Y evolution …

Introduction Sex chromosomes originate from ordinary autosomes. Ancient sex-specific W or
Y chromosomes, like that of female chicken or those of male mammals, usually have lost …

After birds diverged from mammals, different ancestral autosomes evolved into sex
chromosomes in each lineage. In birds, females are ZW and males are ZZ, but in mammals …

Although the genetic triggers for gonadal sex differentiation vary across species, the cell
biology of gonadal development was long thought to be largely conserved. Here, we present …

Numerous methods have been developed to analyse RNA sequencing (RNA-seq) data, but
most rely on the availability of a reference genome, making them unsuitable for non-model …

Background Transcriptomic analysis is crucial for understanding the functional elements of
the genome, with the classic method consisting of screening transcriptomics datasets for …

The typically repetitive nature of the sex-limited chromosome means that it is often excluded
from or poorly covered in genome assemblies, hindering studies of evolutionary and …