The role of intestinal permeability in gastrointestinal disorders and current methods of evaluation

T Vanuytsel, J Tack, R Farre - Frontiers in Nutrition, 2021 - frontiersin.org
An increased intestinal permeability has been described in various gastrointestinal and non-
gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability …

Necrotizing enterocolitis: new insights into pathogenesis and mechanisms

DF Niño, CP Sodhi, DJ Hackam - Nature reviews Gastroenterology & …, 2016 - nature.com
Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal
tract of preterm infants. At present, NEC is thought to develop in the premature host in the …

Current research on the epidemiology, pathogenesis, and management of necrotizing enterocolitis

S Eaton, CM Rees, NJ Hall - Neonatology, 2017 - karger.com
Despite decades of research on necrotizing enterocolitis, we still do not fully understand the
pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of …

Current status of laboratory and imaging diagnosis of neonatal necrotizing enterocolitis

G D'Angelo, P Impellizzeri, L Marseglia… - Italian journal of …, 2018 - Springer
Necrotizing enterocolitis continues to be a devastating disease process for very low birth
weight infants in Neonatal Intensive Care Units. The aetiology and pathogenesis of …

Surgical necrotizing enterocolitis: association between surgical indication, timing, and outcomes

GS Bethell, M Knight, NJ Hall - Journal of Pediatric Surgery, 2021 - Elsevier
Abstract Background/Purpose Despite improvements in neonatal care the outcomes of
Necrotizing Enterocolitis (NEC) remain unchanged over previous decades. The study aims …

Biomarkers of gut injury in neonates–where are we in predicting necrotising enterocolitis?

C Howarth, J Banerjee, S Eaton… - Frontiers in Pediatrics, 2022 - frontiersin.org
Despite advances in neonatal care Necrotising Enterocolitis (NEC) continues to have a
significant mortality and morbidity rate, and with increasing survival of those more immature …

Clinical characteristics and potential pathogenesis of cardiac necrotizing enterocolitis in neonates with congenital heart disease: a narrative review

KY Burge, A Gunasekaran, MM Makoni, AM Mir… - Journal of clinical …, 2022 - mdpi.com
Neonates with congenital heart disease (CHD) are at an increased risk of developing
necrotizing enterocolitis (NEC), an acute inflammatory intestinal injury most commonly …

A spotlight on intestinal permeability and inflammatory bowel diseases

T Rath, R Atreya, MF Neurath - Expert Review of Gastroenterology …, 2023 - Taylor & Francis
Introduction The intestinal barrier is a multi-faced structure lining the surface of the intestinal
mucosa of the GI tract. To exert its main functions as a physical and immunological defense …

Potential Modulation of Inflammation by Probiotic and Omega-3 Supplementation in Elderly with Chronic Low-Grade Inflammation—A Randomized, Placebo …

L Tingö, AN Hutchinson, C Bergh, L Stiefvatter… - Nutrients, 2022 - mdpi.com
Probiotic and omega-3 supplements have been shown to reduce inflammation, and dual
supplementation may have synergistic health effects. We investigated if the novel …

The role of gastrointestinal-related fatty acid-binding proteins as biomarkers in gastrointestinal diseases

SSC Ho, JI Keenan, AS Day - Digestive Diseases and Sciences, 2020 - Springer
The fatty acid-binding proteins play a major role in intracellular transportation of long-chain
fatty acids. Nine fatty acid-binding proteins have been identified, with each having individual …