The role of Notch signaling in the mammalian ovary

DA Vanorny, KE Mayo - Reproduction, 2017 - rep.bioscientifica.com
The Notch pathway is a contact-dependent, or juxtacrine, signaling system that is conserved
in metazoan organisms and is important in many developmental processes. Recent …

Why double ovarian stimulation in an in vitro fertilization cycle is potentially unsafe

A Tocci - Human Reproduction, 2022 - academic.oup.com
The occurrence of two antral follicle recruitment waves in a single inter-ovulatory interval has
been detected in ovaries of normal women. This data supports the claim that a double …

Potential Involvement of DNA Methylation in Hybrid Sterility in Hermaphroditic Argopecten Scallops

T Yu, J Ning, M Chen, F Wang, G Liu, Q Wang, X Xu… - Marine …, 2023 - Springer
DNA methylation is an important epigenetic modification factor in regulating fertility.
Corresponding process remains poorly investigated in hermaphroditic scallops. The …

Dysregulation of lysyl oxidase expression in lesions and endometrium of women with endometriosis

LA Ruiz, PM Báez-Vega, A Ruiz… - Reproductive …, 2015 - journals.sagepub.com
Lysyl oxidases (LOXs) are enzymes involved in collagen deposition, extracellular
membrane remodeling, and invasive/metastatic potential. Previous studies reveal an …

Effects of Notch2 on proliferation, apoptosis and steroidogenesis in bovine luteinized granulosa cells

Y Li, J Jing, W Dang, Q Han, X Guo, K Jia, Y Cheng… - Theriogenology, 2021 - Elsevier
Notch signaling pathway plays an important regulatory role in the development of
mammalian follicles. This study aimed to explore the effect of Notch2 on the function of …

[HTML][HTML] Utilization of the Bologna criteria: a promise unfulfilled? A review of published and unpublished/ongoing trials

A Boza, SY Oguz, S Misirlioglu, K Yakin, B Urman - Fertility and Sterility, 2018 - Elsevier
Objective To study the use of the Bologna criteria (BC) for the definition of poor ovarian
responders (POR) in clinical practice and research. Design Systematic review of published …

Induction of apoptosis by Centaurea nerimaniae extract in HeLa and MDA-MB-231 cells by a caspase-3 pathway

S Kayacan, LT Sener, G Melikoglu… - Biotechnic & …, 2018 - Taylor & Francis
We investigated the cytotoxic and apoptotic effects of a methanol extract of Centaurea
nerimaniae, a plant endemic in Turkey, on HeLa and MDA-MB-231 cells. Eight …

Functional evidence implicating NOTCH2 missense mutations in primary ovarian insufficiency etiology

LC Patiño, I Beau, A Morel, B Delemer… - Human …, 2019 - Wiley Online Library
Primary ovarian insufficiency (POI) is a frequently occurring disease affecting women under
40 years old. Recently, we have analyzed unrelated POI women via whole exome …

Notch signaling pathway in cumulus cells reflecting zygote and embryo quality in polycystic ovary syndrome

M Masoudi, N Yamini, F Salehi, R Aflatoonian… - Archives of Gynecology …, 2021 - Springer
Purpose The present study aimed to explore the associations between the expression
pattern of molecules in the Notch pathway in the cumulus cells of polycystic ovary syndrome …

Biomarkers Assessing the Role of Cumulus Cells on IVF Outcomes: A Systematic Review

G Massoud, M Spann, KC Vaught, S Das… - Journal of Assisted …, 2024 - Springer
Purpose Although significant improvements in assisted reproductive technology (ART)
outcomes have been accomplished, a critical question remains: which embryo is most likely …