Azithromycin (AZM) is a macrolide antibiotic used for the treatment of various bacterial
infections. The drug is known to have low oral bioavailability (37%) which may be attributed …

Guided bone regeneration (GBR) is a surgical procedure utilizing occlusive membranes for
providing space maintenance and enabling selective repopulation of the damaged area …

As the presence of emergent contaminants in wastewater, such as antibiotics, has become a
threat for public health, the evaluation of strategies to treat them has been gaining …

In situ gels have been developed as an innovative strategy to prolong corneal residence
time and enhance drug absorption compared to traditional eye drops. Our study aimed to …

Azithromycin (AZM) is a poorly soluble macrolide antibacterial agent. Its low solubility is
considered as the major contributing factor to its relatively low oral bioavailability. The aim of …

Cocrystallization is a promising approach to alter physicochemical properties of active
pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile. Nowadays …

The objective of the present study was to investigate the effects of processing variables and
formulation factors on the characteristics of hot-melt extrudates containing a copolymer …

The application of small molecular weight compounds may be a way to overcome some of
the drawbacks of polymer-based amorphous solid dispersions, such as drug—polymer …

Azithromycin (AZI) belongs to the class of macrolide antibiotics that has limited water
solubility and belongs to Biopharmaceutical Classification System Class II. Dissolution is the …

The aim of the present study was to improve the solubility and dissolution rate of atorvastatin
(ATV), a slight water-soluble drug, by solid dispersion (SD) technique using a hydrophilic …