New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics

M Mlakić, T Čadež, G Šinko, I Škorić, Z Kovarik - Biomolecules, 2024 - mdpi.com
New furan, thiophene, and triazole oximes were synthesized through several-step reaction
paths to investigate their potential for the development of central nervous systems (CNS) …

1-(4-Nitrophenyl)-1H-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

T Opsomer, K Valkeneers, A Ratković, W Dehaen - Organics, 2021 - mdpi.com
1, 2, 3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an
important role in the discovery of novel applications of the 1, 2, 3-triazole moiety. In this work …

Substituents affect the mechanism of photochemical EZ isomerization of diarylethene triazoles via adiabatic singlet excited state pathway or via triplet excited state

M Mlakić, L Mandić, N Basarić, B Mihaljević… - … of Photochemistry and …, 2022 - Elsevier
Photochemical reactivity in the ZE isomerization for two heterostilbene derivatives
containing 1, 2, 3-triazole unit were investigated theoretically and experimentally by …

New Charged Cholinesterase Inhibitors: Design, Synthesis, and Characterization

M Mlakić, D Barić, A Ratković, I Šagud, I Čipor… - Molecules, 2024 - mdpi.com
Triazoles and triazolium salts are very common subunits in the structures of various drugs.
Medicaments with a characteristic 1, 2, 3-triazole core are also being developed to treat …

Priprava i biološka aktivnost novih tienobenzo-triazola

I Selec - 2023 - zir.nsk.hr
Sažetak Cilj rada bio je sintetizirati nove tienobenzo-triazole te ispitati njihovu inhibicijsku
potenciju prema kolinesterazama. Također je procijenjena selektivnost njihove inhibicije, a …

Synthesis, photochemistry and biological activity of new 1, 2, 3-triazolostilbenes. An experimental and computational study

M Mlakić, I Odak, S Talić, I Faraho, M Bosnar… - 27. hrvatski skup …, 2021 - croris.hr
Sažetak Triazoles present an important class of heterocyclic compounds exhibiting a wide
range of pharmacological activities [1]. New 1, 2, 3-triazolostilbenes were synthesized and …