Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

Ferroptosis is of great significance for disease treatment and drug design because of its
effective damage to drug-resistant cells. However, ferroptosis-based therapy presents …

The rapid development of treatment resistance in tumors poses a technological bottleneck in
clinical oncology. Ferroptosis is a form of regulated cell death with clinical translational …

Recently, there is growing interest in the natural bioactive components having anticancer
activity. Thymoquinone (TQ), the principle active constituent of black seed (Nigella sativa) …

Doxorubicin (DOX) is extensively applied in cancer therapy due to its efficacy in suppressing
cancer progression and inducing apoptosis. After its discovery, this chemotherapeutic agent …

Doxorubicin is a drug that belongs to the anthracycline antibiotics. Nephrotoxicity is one of
the serious side effects of doxorubicin treatment. Crocin, which is one of the most bioactive …

With the continuous development of cancer nanotechnology, an important trend in the
research is to combine the broad application prospects of functional nanomaterials with …

Dioscin shows active effects against renal ischemia/reperfusion injury and
lipopolysaccharide-induced inflammatory kidney injury, however, little is known concerning …

OBJECTIVES: This study was conducted to determine whether the blood pressure-lowering
effect of Nigella sativa might be mediated by its effects on nitric oxide, angiotensin …