Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention

YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …

A global view of the genetic basis of Alzheimer disease

C Reitz, MA Pericak-Vance, T Foroud… - Nature Reviews …, 2023 - nature.com
The risk of Alzheimer disease (AD) increases with age, family history and informative genetic
variants. Sadly, there is still no cure or means of prevention. As in other complex diseases …

Blood-based biomarkers for Alzheimer's disease diagnosis and progression: an overview

A Varesi, A Carrara, VG Pires, V Floris, E Pierella… - Cells, 2022 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disease characterized by
amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain …

The epigenetics of Alzheimer's disease: factors and therapeutic implications

X Liu, B Jiao, L Shen - Frontiers in genetics, 2018 - frontiersin.org
Alzheimer's disease (AD) is a well-known neurodegenerative disorder that imposes a great
burden on the world. The mechanisms of AD are not yet fully understood. Current insight into …

Small non-coding RNAs: new class of biomarkers and potential therapeutic targets in neurodegenerative disease

CN Watson, A Belli, V Di Pietro - Frontiers in genetics, 2019 - frontiersin.org
Neurodegenerative diseases (NDs) are becoming increasingly prevalent in the world, with
an aging population. In the last few decades, due to the devastating nature of these …

MicroRNAs in Alzheimer's disease: diagnostic markers or therapeutic agents?

F Angelucci, K Cechova, M Valis, K Kuca… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding nucleic acids able to post-transcriptionally
regulate gene expression by binding to complementary sequences of target messenger …

Emerging role and therapeutic implication of mTOR signalling in intervertebral disc degeneration

HW Chen, JW Zhou, GZ Zhang, ZB Luo, L Li… - Cell …, 2023 - Wiley Online Library
Intervertebral disc degeneration (IDD), an important cause of chronic low back pain (LBP), is
considered the pathological basis for various spinal degenerative diseases. A series of …

[PDF][PDF] Long noncoding RNA NEAT1 aggravates Aβ-induced neuronal damage by targeting miR-107 in Alzheimer's disease

S Ke, Z Yang, F Yang, X Wang, J Tan… - Yonsei medical …, 2019 - synapse.koreamed.org
Purpose Alzheimer's disease (AD) is the most common neurodegenerative disease, with a
rising prevalence worldwide. Long noncoding RNAs (lncRNAs) have been found to play …

Circular RNA circ_0000950 promotes neuron apoptosis, suppresses neurite outgrowth and elevates inflammatory cytokines levels via directly sponging miR-103 in …

H Yang, H Wang, H Shang, X Chen, S Yang, Y Qu… - Cell Cycle, 2019 - Taylor & Francis
This study aimed to investigate the effect of circ_0000950/miR-103 network on regulating
neuron apoptosis, neurite outgrowth and inflammation in Alzheimer's disease (AD). Cellular …

Hearing loss, tinnitus, hyperacusis, and diplacusis in professional musicians: A systematic review

A Di Stadio, L Dipietro, G Ricci, A Della Volpe… - International journal of …, 2018 - mdpi.com
Professional musicians (PMs) are at high risk of developing hearing loss (HL) and other
audiological symptoms such as tinnitus, hyperacusis, and diplacusis. The aim of this …