[HTML][HTML] Monkeypox: disease epidemiology, host immunity and clinical interventions

FM Lum, A Torres-Ruesta, MZ Tay, RTP Lin… - Nature Reviews …, 2022 - nature.com
Monkeypox virus (MPXV), which causes disease in humans, has for many years been
restricted to the African continent, with only a handful of sporadic cases in other parts of the …

[HTML][HTML] Monkeypox: a new threat?

D Kmiec, F Kirchhoff - International journal of molecular sciences, 2022 - mdpi.com
The global vaccination programme against smallpox led to its successful eradication and
averted millions of deaths. Monkeypox virus (MPXV) is a close relative of the Variola …

[HTML][HTML] Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

J Isidro, V Borges, M Pinto, D Sobral, JD Santos… - Nature medicine, 2022 - nature.com
The largest monkeypox virus (MPXV) outbreak described so far in non-endemic countries
was identified in May 2022 (refs.,,,,–). In this study, shotgun metagenomics allowed the rapid …

Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb. 1 in a small animal model

JL Americo, PL Earl, B Moss - Proceedings of the National …, 2023 - National Acad Sciences
Human mpox (monkeypox), a disease with similarities to smallpox, is endemic in Africa
where it has persisted as a zoonosis with limited human-to-human spread. Unexpectedly …

Phylogenomic analysis of the monkeypox virus (MPXV) 2022 outbreak: Emergence of a novel viral lineage?

N Luna, AL Ramírez, M Muñoz, N Ballesteros… - Travel medicine and …, 2022 - Elsevier
Monkeypox is a zoonotic disease with clinical manifestations similar to smallpox in humans.
Since May 13, 2022, an increasing number of suspected and confirmed cases have been …

[HTML][HTML] Monkeypox (mpox) virus: Classification, origin, transmission, genome organization, antiviral drugs, and molecular diagnosis

A Karagoz, H Tombuloglu, M Alsaeed… - Journal of infection and …, 2023 - Elsevier
Monkeypox virus (MPXV) is a double-stranded DNA virus belonging to the Poxviridae family
of the genus Orthopoxvirus with two different clades known as West African and Congo …

Ultrasensitive and specific clustered regularly interspaced short palindromic repeats empowered a plasmonic fiber tip system for amplification-free monkeypox virus …

Y Chen, Z Chen, T Li, M Qiu, J Zhang, Y Wang… - ACS …, 2023 - ACS Publications
The urgent necessity for highly sensitive diagnostic tools has been accentuated by the
ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying …

[HTML][HTML] Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in Portugal

V Borges, MP Duque, JV Martins, P Vasconcelos… - Nature Medicine, 2023 - nature.com
Pathogen genome sequencing during epidemics enhances our ability to identify and
understand suspected clusters and investigate their relationships. Here, we combine …

APOBEC3 deaminase editing in mpox virus as evidence for sustained human transmission since at least 2016

Á O'Toole, RA Neher, N Ndodo, V Borges, B Gannon… - Science, 2023 - science.org
Historically, mpox has been characterized as an endemic zoonotic disease that transmits
through contact with the reservoir rodent host in West and Central Africa. However, in May …

Monkeypox virus infections in humans

S Elsayed, L Bondy, WP Hanage - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Human monkeypox is a viral zoonosis endemic to West and Central Africa that has recently
generated increased interest and concern on a global scale as an emerging infectious …