BACKGROUND Conformational changes are essential for the correct functioning of
biological macromolecules. Time-resolved x-ray crystallography extends an extremely …

Thanks to recent technological advances in X-ray and micro-electron diffraction and solid-
state NMR, structural information can be obtained by using much smaller crystals. Thus …

High-intensity femtosecond pulses from an X-ray free-electron laser enable pump–probe
experiments for the investigation of electronic and nuclear changes during light-induced …

In this work we present experiments and simulations on the nucleation and successive
dynamics of laser-induced bubbles inside liquid droplets in free-fall motion, ie a case where …

Here, we illustrate what happens inside the catalytic cleft of an enzyme when substrate or
ligand binds on single-millisecond timescales. The initial phase of the enzymatic cycle is …

The high intensity of X-ray free electron lasers (XFELs) can damage solution-phase samples
on every scale, ranging from the molecular or electronic structure of a sample to the …

The Sample Environment and Characterization (SEC) group of the European X-ray Free-
Electron Laser (EuXFEL) develops sample delivery systems for the various scientific …

Proteins guide the flows of information, energy, and matter that make life possible by
accelerating transport and chemical reactions, by allosterically modulating these reactions …

One of the primary objectives in chemistry research is to observe atomic motions during
reactions in real time. Although X-ray free-electron lasers (XFELs) have facilitated the …

The X-ray free-electron laser (XFEL) has remarkably advanced X-ray imaging technology
and enabled important scientific achievements. The XFEL's extremely high power, short …