Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking

L Zhang, X Wei, Z Wang, P Liu, Y Hou, Y Xu, H Su… - Cell Reports, 2023 - cell.com
It is widely known that stimulator of interferon genes (STING) can trigger nuclear factor κB
(NF-κB) signaling. However, whether and how the NF-κB pathway affects STING signaling …

Coumarin derivatives in inflammatory bowel disease

LC Di Stasi - Molecules, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a non-communicable disease characterized by a
chronic inflammatory process of the gut and categorized into Crohn's disease and ulcerative …

Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis

M Xu, J Tao, Y Yang, S Tan, H Liu, J Jiang… - Cell Death & …, 2020 - nature.com
Ferroptosis has recently emerged as an iron-dependent form of nonapoptotic cell death,
which is also a regulated necrosis process and a response to tumor suppression. However …

[HTML][HTML] Systemic inflammation in preclinical ulcerative colitis

D Bergemalm, E Andersson, J Hultdin, C Eriksson… - Gastroenterology, 2021 - Elsevier
Background & Aims Preclinical ulcerative colitis is poorly defined. We aimed to characterize
the preclinical systemic inflammation in ulcerative colitis, using a comprehensive set of …

Bacteroides vulgatus attenuates experimental mice colitis through modulating gut microbiota and immune responses

L Liu, M Xu, R Lan, D Hu, X Li, L Qiao, S Zhang… - Frontiers in …, 2022 - frontiersin.org
Introduction Bacteroides vulgatus is one of the predominant Bacteroides species in the
human gut and exerts a series of beneficial effects. The aim of this study was to investigate …

2-O-β-d-Glucopyranosyl-l-ascorbic Acid, an Ascorbic Acid Derivative Isolated from the Fruits of Lycium Barbarum L., Modulates Gut Microbiota and Palliates Colitis …

K Huang, W Dong, W Liu, Y Yan, P Wan… - Journal of agricultural …, 2019 - ACS Publications
In this study, the effects of 2-O-β-d-glucopyranosyl-l-ascorbic acid (AA-2βG), a natural
ascorbic acid derivative from the fruits of Lycium barbarum, on treating the dextran sulfate …

Probiotics interact with lipids metabolism and affect gut health

T Wu, G Wang, Z Xiong, Y Xia, X Song, H Zhang… - Frontiers in …, 2022 - frontiersin.org
Probiotics have attracted much attention due to their ability to modulate host intestinal
microbe, participate in nutrient metabolism or immunomodulatory. Both inflammatory bowel …

Febuxostat attenuates ulcerative colitis by the inhibition of NF-κB, proinflammatory cytokines, and oxidative stress in mice

K Amirshahrokhi - International Immunopharmacology, 2019 - Elsevier
Ulcerative colitis is a chronic inflammatory disorder characterized by oxidative stress and
upregulation of proinflammatory mediators in colonic tissue. Febuxostat, a xanthine oxidase …

[HTML][HTML] Molecular and cellular mechanisms influenced by postbiotics

R Jastrząb, D Graczyk, P Siedlecki - International journal of molecular …, 2021 - mdpi.com
In recent years, commensal bacteria colonizing the human body have been recognized as
important determinants of health and multiple pathologic conditions. Among the most …