Zebrafish as a successful animal model for screening toxicity of medicinal plants

A Modarresi Chahardehi, H Arsad, V Lim - Plants, 2020 - mdpi.com
The zebrafish (Danio rerio) is used as an embryonic and larval model to perform in vitro
experiments and developmental toxicity studies. Zebrafish may be used to determine the …

Scale-up approach for supercritical fluid extraction with ethanol–water modified carbon dioxide on Phyllanthus niruri for safe enriched herbal extracts

N Hassim, M Markom, MI Rosli, S Harun - Scientific reports, 2021 - nature.com
Scaling-up supercritical fluid extraction (SFE) for the extraction of bioactive compounds from
herbal plants is challenging, especially with the presence of alcohol-water as co-solvent …

[HTML][HTML] Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Insights into Alzheimer's disease models through anxiety and locomotion testing, and acute …

SZ Raduan, QU Ahmed, AR Kasmuri… - Journal of King Saud …, 2023 - Elsevier
Alzheimer's disease (AD) is a complicated neurodegenerative disorder that presents
significant challenges for the development of effective therapeutic interventions …

Bioactivity assay of microalgae: antioxidant and antidiabetic potentials in a transgenic zebrafish model

TH Toranposhti, FS Hosseini, M Rezaei… - Applied Food …, 2024 - journals.sbmu.ac.ir
Abstract Background and Objective: Microalgae with antioxidant, alpha-amylase and alpha-
glucosidase inhibition and NF-κB activation abilities have shown promising anti-diabetic …

[PDF][PDF] Antidiabetic, hypolipidemic, antioxidant and anti-inflammatory effects of Momordica charantia L. foliage extract

AL Parra, RM Soto-del Valle, JP Ferrer… - J Pharm …, 2021 - academia.edu
Abstract Resumen Context: Momordica charantia (Cucurbitaceae) is extensively distributed
in tropical areas, and it is traditionally used as antidiabetic. Nevertheless, few studies …

[HTML][HTML] Acute and sub-acute oral toxicity Lagerstroemia speciosa in Sprague-Dawley rats

S Alkahtani, MS Hasnain, H Algamdy… - Saudi Journal of …, 2022 - Elsevier
Through the boost of the natural medicinal market, individuals began to use a variety of
organic materials in the marketed herbal preparation. Lagerstroemia speciosa (LS) leaves …

Acute Toxicity of Leaf Extracts of Enydra fluctuans Lour in Zebrafish (Danio rerio Hamilton)

J Xavier, K Kripasana - Scientifica, 2020 - Wiley Online Library
The present study was focused on the concentration‐dependent changes in oral acute
toxicity of leaf extracts of E. fluctuans in zebrafish. The study was also aimed at the details of …

Elicitation of apigenin in green leafy vegetable plants and its molecular docking evaluation for effective anticancer applications

T Keerthanaa, S Boobalan, D Kamalanathan… - Plant Cell, Tissue and …, 2022 - Springer
Elicitors are generally recognized as safe substances and application to crops is effective for
stimulating the biosynthesis of health-promoting phytochemicals. The study includes six …

Momordica charantia L. for hyperlipidaemia: A randomised controlled assessment of the Ghanaian herbal medicinal product MCP-1

KP Thomford, AK Thomford, J Yorke, R Yeboah… - Journal of Herbal …, 2021 - Elsevier
Cardiovascular diseases are a public health burden for developing countries like Ghana.
Scientifically validated herbal medicines are viable options in the prevention and treatment …

[HTML][HTML] Exploring the neuropharmacological properties of scopoletin-rich Evolvulus alsinoides extract using in-silico and in-vitro methods

S Ather, C Bhattacharyya, H Gupta, Y Patil… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objectives: This study investigates the neuropharmacologic properties of Scopoletin, a
bioactive compound in Evolvulus alsinoides (EA) extract, for managing cognitive impairment …