Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …
It has been posited SARS-CoV-2 contains at least one unique superantigen-like motif not found in any other SARS or endemic coronaviruses. Superantigens are potent antigens that …
M Karbalaeimahdi, S Farajnia, N Bargahi… - Journal of Interferon & …, 2023 - liebertpub.com
Although the new generation of vaccines and anti-COVID-19 treatment regimens facilitated the management of acute COVID-19 infections, concerns about post-COVID-19 syndrome or …
Bacterial T cell superantigens (SAgs) are a family of microbial exotoxins that function to activate large numbers of T cells simultaneously. SAgs activate T cells by direct binding and …
JR Hurst, KJ Kasper, AN Sule, JK McCormick - Infection, Genetics and …, 2018 - Elsevier
Streptococcus pyogenes is a human-specific and globally prominent bacterial pathogen that despite causing numerous human infections, this bacterium is normally found in an …
Autoimmunity involves immune responses directed against self, which are a result of defective self/foreign distinction of the immune system, leading to proliferation of self …
P Wang, Z Fredj, H Zhang, G Rong… - Journal of …, 2024 - Wiley Online Library
Superantigens are virulence factors secreted by microorganisms that can cause various immune diseases, such as overactivating the immune system, resulting in cytokine storms …
N Chen, Y Dai, J He, M Zhou, H Sun, L Lin, F Gao… - Medicine, 2023 - journals.lww.com
Background: The relationship between transforming growth factor-β1 (TGF-β1) gene polymorphisms and systemic lupus erythematosus (SLE) has been reported in many …