Rational design of cancer nanomedicine: nanoproperty integration and synchronization

Q Sun, Z Zhou, N Qiu, Y Shen - Advanced materials, 2017 - Wiley Online Library
Current cancer nanomedicines can only mitigate adverse effects but fail to enhance
therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …

Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release

N Kamaly, B Yameen, J Wu, OC Farokhzad - Chemical reviews, 2016 - ACS Publications
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

VP Torchilin - Nature reviews Drug discovery, 2014 - nature.com
The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the
in vivo effectiveness of drugs is now well established. The development of multifunctional …

Transformable liquid-metal nanomedicine

Y Lu, Q Hu, Y Lin, DB Pacardo, C Wang, W Sun… - Nature …, 2015 - nature.com
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

R Cheng, F Meng, C Deng, HA Klok, Z Zhong - Biomaterials, 2013 - Elsevier
In the past decades, polymeric nanoparticles have emerged as a most promising and viable
technology platform for targeted and controlled drug delivery. As vehicles, ideal …

Cationic polymers and their therapeutic potential

SK Samal, M Dash, S Van Vlierberghe… - Chemical Society …, 2012 - pubs.rsc.org
The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

Multi-stimuli responsive macromolecules and their assemblies

J Zhuang, MR Gordon, J Ventura, L Li… - Chemical Society …, 2013 - pubs.rsc.org
In this review, we outline examples that illustrate the design criteria for achieving
macromolecular assemblies that incorporate a combination of two or more chemical …

Design and development of polymeric micelles with cleavable links for intracellular drug delivery

H Wei, RX Zhuo, XZ Zhang - Progress in polymer Science, 2013 - Elsevier
Driven by the urgent need in practical applications of stimuli-responsive nano-carriers for
intracellular drug delivery, the design and development of advanced polymeric micelles …

Antibacterial material surfaces/interfaces for biomedical applications

Y Wang, F Wang, H Zhang, B Yu, H Cong… - Applied Materials Today, 2021 - Elsevier
Biomaterial central infection (BCI) is a tough problem that has attracted high attention. The
most common source of infection in biomaterial centers is bacterial infections. For the past …

Redox and pH-responsive degradable micelles for dually activated intracellular anticancer drug release

W Chen, P Zhong, F Meng, R Cheng, C Deng… - Journal of controlled …, 2013 - Elsevier
Redox and pH dual-responsive biodegradable micelles were developed based on poly
(ethylene glycol)-SS-poly (2, 4, 6-trimethoxybenzylidene-pentaerythritol carbonate)(PEG-SS …