Droplet-based microfluidics in biomedical applications

L Amirifar, M Besanjideh, R Nasiri, A Shamloo… - …, 2022 - iopscience.iop.org
Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …

Microfluidic synthesis control technology and its application in drug delivery, bioimaging, biosensing, environmental analysis and cell analysis

CT Kung, H Gao, CY Lee, YN Wang, W Dong… - Chemical Engineering …, 2020 - Elsevier
Nanomaterials have attracted significant attention in biomedical and environmental science
in recent years due to their unique thermal, optical, electrical and magnetic properties. The …

Experimental investigation of on-demand ferrofluid droplet generation in microfluidics using a Pulse-Width Modulation magnetic field with proposed correlation

MA Bijarchi, A Favakeh, S Alborzi, MB Shafii - Sensors and Actuators B …, 2021 - Elsevier
Micro-magnetofluidics offers a promising tool to regulate the drop formation process with
versatile applications in engineering and biomedicine. In the present study, on-demand …

Chiral lipid bilayers are enantioselectively permeable

J Hu, WG Cochrane, AX Jones, DG Blackmond… - Nature …, 2021 - nature.com
Homochiral membrane bilayers organize biological functions in all domains of life. The
membrane's permeability—its key property—correlates with a molecule's lipophilicity, but the …

Physicochemical characteristics of droplet interface bilayers

Y Huang, GG Fuller, VC Suja - Advances in Colloid and Interface Science, 2022 - Elsevier
Droplet interface bilayer (DIB) is a lipid bilayer formed when two lipid monolayer-coated
aqueous droplets are brought in contact within an oil phase. DIBs, especially post …

Lipid Microfluidic Biomimetic Models for Drug Screening: A Comprehensive Review

E Fernandes, VF Cardoso… - Advanced Functional …, 2024 - Wiley Online Library
Developing new drugs is a complex, time‐consuming, and expensive process, essential to
identify potential pharmacokinetic issues in the early stages to avoid investment in …

UV-DIB: label-free permeability determination using droplet interface bilayers

R Strutt, F Sheffield, NE Barlow, AJ Flemming… - Lab on a Chip, 2022 - pubs.rsc.org
Simple diffusion of molecular entities through a phospholipid bilayer, is a phenomenon of
great importance to the pharmaceutical and agricultural industries. Current model lipid …

Droplet-based membranous soft materials

MM Makhoul-Mansour, EC Freeman - Langmuir, 2021 - ACS Publications
Inspired by the structure and functionality of natural cellular tissues, droplet interface bilayer
(DIB)-based materials strategically combine model membrane assembly techniques and …

Microfluidic platform enables tailored translocation and reaction cascades in nanoliter droplet networks

S Bachler, D Haidas, M Ort, TA Duncombe… - Communications …, 2020 - nature.com
In the field of bottom-up synthetic biology, lipid membranes are the scaffold to create minimal
cells and mimic reactions and processes at or across the membrane. In this context, we …

A bespoke microfluidic pharmacokinetic compartment model for drug absorption using artificial cell membranes

JL Korner, EB Stephenson, KS Elvira - Lab on a Chip, 2020 - pubs.rsc.org
Early prediction of the rate and extent of intestinal absorption is vital for the efficient
development of orally administered drugs. Here we show a new type of pharmacokinetic …