The intrinsic limits of conventional cancer therapies prompted the development and
application of various nanotechnologies for more effective and safer cancer treatment …

Navigation through the bulk tumour, entry into the blood vasculature, survival in the
circulation, exit at distant sites and resumption of proliferation are all steps necessary for …

Therapeutic nanoparticles (TNPs) aim to deliver drugs more safely and effectively to
cancers, yet clinical results have been unpredictable owing to limited in vivo understanding …

The principles of engineering and physics have been applied to oncology for nearly 50
years. Engineers and physical scientists have made contributions to all aspects of cancer …

Palladium catalysts have been widely adopted for organic synthesis and diverse industrial
applications given their efficacy and safety, yet their biological in vivo use has been limited …

Involvement of the immune system in tumour progression is at the forefront of cancer
research. Analysis of the tumour immune microenvironment has yielded a wealth of …

Small molecule drugs that target microtubules (MTs), many of them natural products, have
long been important tools in the MT field. Indeed, tubulin (Tb) was discovered, in part, as the …

Imaging reveals complex structures and dynamic interactive processes, located deep inside
the body, that are otherwise difficult to decipher. Numerous imaging modalities harness …

Mass spectrometry imaging (MSI) is emerging as a powerful analytical tool for detection,
quantification, and simultaneous spatial molecular imaging of endogenous and exogenous …

Imaging, including its use for innovative tissue sampling, is slowly being recognized as
playing a pivotal role in drug development, clinical trial design, and more effective delivery …