Cardiovascular disease is a leading cause of death worldwide and accounts for> 17.3
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …

Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …

Background—Perivascular adipose tissue (PVAT) surrounds most vessels and shares
common features with brown adipose tissue (BAT). Although adaptive thermogenesis in BAT …

Adipose tissues are present at multiple locations in the body. Most blood vessels are
surrounded with adipose tissue which is referred to as perivascular adipose tissue (PVAT) …

As the central pacemaker, the suprachiasmatic nucleus (SCN) has long been considered
the primary regulator of blood pressure circadian rhythm; however, this dogma has been …

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease. BAF60c, a unique
subunit of the SWItch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex, is …

Metabolic syndrome (MetS) is a constellation of risk factors including insulin resistance,
central obesity, dyslipidemia and hypertension that markedly increase the risk of Type 2 …

Background: The perivascular adipose tissue (PVAT) surrounding vessels constitutes a
distinct functional integral layer of the vasculature required to preserve vascular tone under …

Background: Abdominal aortic aneurysm (AAA) is a severe aortic disease with a high
mortality rate in the event of rupture. Pharmacological therapy is needed to inhibit AAA …

Rationale: Nitro-oleic acid (OA-NO2) is a bioactive, nitric-oxide derived fatty acid with
physiologically relevant vasculoprotective properties in vivo. OA-NO2 exerts cell signaling …