Alzheimer's disease (AD) is one of the most devastating neurodegenerative diseases. It has
been known for decades that the APOE ɛ 4 allele is the most significant genetic risk factor …

Major advances have been made in our understanding of the role of apolipoprotein E
(apoE) in the onset and development of atherosclerosis. Increasing evidence from both …

A role for β-amyloid precursor protein (β-APP) in the development of Alzheimer's disease
has been indicated by genetics, and many conditions in which β-APP is raised have been …

A relationship between the apolipoprotein E (apoE) genotype and the risk to develop
Alzheimer's disease has been established recently. Apolipoprotein synthesis is implicated in …

Apolipoprotein E plays an important role in recovery from acute brain injury and risk of
developing Alzheimer's disease. We demonstrate that biologically relevant concentrations of …

Chronically activated glia associated with amyloid plaques might contribute to neuronal
dysfunction in Alzheimer's disease (AD) through generation of neuroinflammatory …

Apolipoprotein E (apoE) influences both innate and acquired immunity in cultured cells. To
determine whether apoE affects the immune system in vivo, Listeria monocytogenes (LM) …

Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of
new information on the use of these peptides as transport systems has in fact served to …

Apolipoprotein E (apoE)-related synthetic peptides, the 22 kDa N-terminal thrombin-
cleavage fragment of apoE (truncated apoE), and full-length apoE have all been shown to …

The epsilon 4 allele of the human apolipoprotein E gene (ApoE4. constitutes an important
genetic risk factor for Alzheimer's disease. Recent experimental evidence suggests that …