Bone is a tissue undergoing continuous building and degradation. This remodelling is a
tightly regulated process that can be disturbed by many factors, particularly hormonal …

The term osteoimmunology was coined many years ago to describe the research field that
deals with the cross-regulation between bone cells and the immune system. As a matter of …

Bone is in a constant state of remodeling, a process which was once attributed solely to
osteoblasts and osteoclasts. Decades of research has identified many other populations of …

Osteoporosis and fractures contribute to damage in one of the most frequently involved
organ systems in patients with systemic lupus erythematosus (SLE): the musculoskeletal …

Inflammation perturbs normal bone homeostasis and is known to induce bone loss, as it
promotes both local cartilage degradation and local and systemic bone destruction by …

Numerous rheumatic diseases, including rheumatoid arthritis, juvenile idiopathic arthritis,
psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus, systemic sclerosis …

Objective Bone marrow–derived mesenchymal stem cells (BM‐MSCs) create a special
microenvironment for hematopoiesis and immunity and display robust immunomodulatory …

Previous studies suggested possible bone loss and fracture risk in patients with systemic
lupus erythematosus (SLE). The aim of this systematic review and meta-analysis was to …

P-glycoprotein (Pgp) is a transmembrane protein of 170 kD encoded by the multidrug
resistance 1 (MDR-1) gene, localized on chromosome 7. More than 50 polymorphisms of the …

Aim: To determine if baseline vitamin D levels would influence the gain in bone mineral
density (BMD) in female systemic lupus erythematosus (SLE) patients on corticosteroids …