Abstract mRNA vaccines have evolved from being a mere curiosity to emerging as COVID- 19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …
During the COVID-19 pandemic, mRNA (mRNA) vaccines emerged as leading vaccine candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
YS Wang, M Kumari, GH Chen, MH Hong… - Journal of Biomedical …, 2023 - Springer
Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a major challenge in realizing this drug class will promise to develop methods for safely …
JM Henderson, A Ujita, E Hill… - Current …, 2021 - Wiley Online Library
Synthetic messenger RNA (mRNA)− based therapeutics are an increasingly popular approach to gene and cell therapies, genome engineering, enzyme replacement therapy …
M Warminski, A Mamot, A Depaix… - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Messenger ribonucleic acid (mRNA) is the universal cellular instruction for ribosomes to produce proteins. Proteins are responsible for most of the functions of living …
Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological preparations developed using this platform. During the pandemic, their administration has …
M Zhang, J Song, W Yuan, W Zhang, Z Sun - Frontiers in immunology, 2021 - frontiersin.org
RNA methylation is a kind of RNA modification that exists widely in eukaryotes and prokaryotes. RNA methylation occurs not only in mRNA but also in ncRNA. According to the …
Messenger RNA (mRNA) has immense potential for developing a wide range of therapies, including immunotherapy and protein replacement. As mRNA presents no risk of integration …
Lipid nanoparticle (LNP) formulated messenger RNA-based (LNP-mRNA) vaccines came into the spotlight as the first vaccines against SARS-CoV-2 virus to be applied worldwide …