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Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

The ZAKα-driven ribotoxic stress response (RSR) is activated by ribosome stalling and/or
collisions. Recent work demonstrates that RSR also plays a role in innate immunity by …

Lung nociceptors initiate cough and bronchoconstriction. To elucidate if these fibers also
contribute to allergic airway inflammation, we stimulated lung nociceptors with capsaicin and …

The developmental origin of oligodendrocyte progenitors (OLPs) in the forebrain has been
controversial. We now show, by Cre-lox fate mapping in transgenic mice, that the first OLPs …

Brown adipose tissue, because of its capacity for uncoupled mitochondria! respiration1, 2,
has been implicated as an important site of facultative energy expenditure3–5. This has led …

Orexins (hypocretins) are a pair of neuropeptides implicated in energy homeostasis and
arousal. Recent reports suggest that loss of orexin-containing neurons occurs in human …

A new system for lineage ablation is based on transgenic expression of a diphtheria toxin
receptor (DTR) in mouse cells and application of diphtheria toxin (DT). To streamline this …

Male reproductive processes in flowering plants take place in the stamen (Esau, 1977). This
sporophytic organ system contains diploid cells that undergo meiosis and produce haploid …