Assessing the safety of stem cell therapeutics

CEP Goldring, PA Duffy, N Benvenisty, PW Andrews… - Cell stem cell, 2011 - cell.com
Unprecedented developments in stem cell research herald a new era of hope and
expectation for novel therapies. However, they also present a major challenge for regulators …

Drosophila provides rapid modeling of renal development, function, and disease

JAT Dow, MF Romero - American Journal of Physiology …, 2010 - journals.physiology.org
The evolution of specialized excretory cells is a cornerstone of the metazoan radiation, and
the basic tasks performed by Drosophila and human renal systems are similar. The …

Injection of amniotic fluid stem cells delays progression of renal fibrosis

S Sedrakyan, S Da Sacco, A Milanesi… - Journal of the …, 2012 - journals.lww.com
Injection of amniotic fluid stem cells ameliorates the acute phase of acute tubular necrosis in
animals by promoting proliferation of injured tubular cells and decreasing apoptosis, but …

In vitro and in vivo cardiomyogenic differentiation of amniotic fluid stem cells

S Bollini, M Pozzobon, M Nobles, J Riegler… - Stem Cell Reviews and …, 2011 - Springer
Cell therapy has developed as a complementary treatment for myocardial regeneration.
While both autologous and allogeneic uses have been advocated, the ideal candidate has …

The fruit fly, Drosophila melanogaster: modeling of human diseases (Part II)

M Allocca, S Zola, P Bellosta - Drosophila melanogaster-Model …, 2018 - books.google.com
The fruit fly, Drosophila melanogaster (Meigen, 1830) has been established as a key model
organism thanks in part to their considerable biological similarity to mammals and an …

Genome-wide analysis reveals the unique stem cell identity of human amniocytes

CT Maguire, BL Demarest, JT Hill, JD Palmer… - PloS one, 2013 - journals.plos.org
Human amniotic fluid contains cells that potentially have important stem cell characteristics,
yet the programs controlling their developmental potency are unclear. Here, we provide …

Whole organ sheep kidney tissue engineering and in vivo transplantation: effects of perfusion-based decellularization on vascular integrity

AM Kajbafzadeh, R Khorramirouz… - Materials Science and …, 2019 - Elsevier
Introduction During the past decade, increased efforts have been made to develop
alternative management options instead of dialysis and homograft renal transplantation for …

An improved kidney dissociation and reaggregation culture system results in nephrons arranged organotypically around a single collecting duct system

V Ganeva, M Unbekandt, JA Davies - Organogenesis, 2011 - Taylor & Francis
Methods for constructing engineered “tissues” from simple suspensions of cells are valuable
for investigations into basic developmental biology and for tissue engineering. We recently …

In situ tissue regeneration of renal tissue induced by collagen hydrogel injection

SJ Lee, HJ Wang, TH Kim, JS Choi… - Stem cells …, 2018 - academic.oup.com
Host stem/progenitor cells can be mobilized and recruited to a target location using
biomaterials, and these cells may be used for in situ tissue regeneration. The objective of …

The use of stem cells in kidney disease

P Chhabra, KL Brayman - Current opinion in organ …, 2009 - journals.lww.com
The use of stem cells in kidney disease : Current Opinion in Organ Transplantation The use of
stem cells in kidney disease : Current Opinion in Organ Transplantation Log in or Register …