Telomerase is a key enzyme for cell survival that prevents telomere shortening and the
subsequent cellular senescence that is observed after many rounds of cell division. In …

Cancer is considered the most important clinical, social and economic issue regarding
cause‑specific disability‑adjusted life years among all human pathologies. Exogenous …

Tumour cells can adopt telomere maintenance mechanisms (TMMs) to avoid telomere
shortening, an inevitable process due to successive cell divisions. In most tumour cells …

Liver cancer is one of the most common cancer types worldwide and the fourth leading
cause of cancer-related death. Liver carcinoma is distinguished by a high heterogeneity in …

Background and aims Plasma circulating tumor DNA (ctDNA) with tumor-specific mutations
is an attractive biomarker. The telomerase reverse transcriptase (TERT) C228T promoter …

Background Hepatocellular carcinoma (HCC) is a fatal disease characterized by early
genetic alterations in telomerase reverse transcriptase promoter (TERTp) and β-catenin …

Simple Summary Hepatocellular carcinoma (HCC) is a deadly form of liver cancer that has
poor patient outcomes and survival. Unlike many other cancers, HCC has not seen the …

The gender disparity of hepatocellular carcinoma (HCC) is most striking in hepatitis B virus
(HBV)‐related cases. The majority of such HCC cases contain integrated HBV, and some …

Simple Summary Telomerase reverse transcriptase (TERT) mutations are the most frequent
genetic alterations in hepatocellular carcinoma (HCC). However, integrative analysis studies …

Majority of patients with resected early-and intermediate-stage liver cancer will experience
postoperative recurrence. This study aimed to investigate the application of ctDNA …