Ovarian infertility and subfertility presenting with premature ovarian insufficiency (POI) and
diminished ovarian reserve are major issues facing the developed world due to the trend of …

Premature ovarian insufficiency (POI) is the depletion of ovarian function before 40 years of
age due to insufficient oocyte formation or accelerated follicle atresia. Approximately 1–5 …

Premature ovarian insufficiency (POI) is a clinically heterogeneous disease that may
seriously affect the physical and mental health of women of reproductive age. POI primarily …

Mutations in DNA damage response (DDR) factors are associated with human infertility,
which affects up to 15% of the population. The DDR is required during germ cell …

The Fanconi anemia pathway is a key pathway involved in the repair of deoxyribonucleic
acidinterstrand crosslinking damage, which chiefly includes the following four modules …

Objectives Hereditary breast and ovarian cancer syndrome is chacterized with multiple
cases of breast cancer and/or ovarian cancer on the same side of the family. BRCA1/BRCA2 …

Purpose To investigate the potential etiologies of premature ovarian insufficiency (POI) and
diminished ovarian reserve (DOR). Methods Fourteen women with sporadic POI and 6 …

Актуальность. Около 30% случаев наследственного рака молочной железы (РМЖ)
обусловлено мутациями в генах BRCA1 и BRCA2. Отсутствие в России программ …

Objective: This study was conducted to evaluate the treatment effectiveness of Chinese
herbal medicine capsules containing the Yangyin Shugan formula (YYSG) in premature …

Background Premature ovarian insufficiency (POI) is a common disease in women that
leads to a reduced reproductive lifespan. The aetiology of POI is genetically heterogeneous …