Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association

BW McCrindle, AH Rowley, JW Newburger, JC Burns… - circulation, 2017 - Am Heart Assoc
Background: Kawasaki disease is an acute vasculitis of childhood that leads to coronary
artery aneurysms in≈ 25% of untreated cases. It has been reported worldwide and is the …

Kawasaki disease

JW Newburger, M Takahashi, JC Burns - Journal of the American College …, 2016 - jacc.org
Kawasaki disease is an acute, self-limited vasculitis of unknown etiology that occurs
predominantly in infants and children. If not treated early with high-dose intravenous …

Dissecting Kawasaki disease: a state-of-the-art review

SM Dietz, D Van Stijn, D Burgner, M Levin… - European journal of …, 2017 - Springer
Kawasaki disease (KD) is a pediatric vasculitis with coronary artery aneurysms (CAA) as its
main complication. The diagnosis is based on the presence of persistent fever and clinical …

The immunomodulatory effects of intravenous immunoglobulin therapy in Kawasaki disease

JC Burns, A Franco - Expert review of clinical immunology, 2015 - Taylor & Francis
The introduction of intravenous immunoglobulin (IVIG) for modulation of inflammation in
acute Kawasaki disease was a great therapeutic triumph. However, three decades later, the …

Genome-wide association study identifies novel susceptibility genes associated with coronary artery aneurysm formation in Kawasaki disease

HC Kuo, SC Li, MMH Guo, YH Huang, HR Yu… - PloS one, 2016 - journals.plos.org
Kawasaki disease (KD) or Kawasaki syndrome is known as a vasculitis of small to medium-
sized vessels, and coronary arteries are predominantly involved in childhood. Generally, 20 …

Metagenomic analysis demonstrates distinct changes in the gut microbiome of Kawasaki diseases children

L Han, X Liu, Y Lan, Y Hua, Z Fan, Y Li - Frontiers in Immunology, 2024 - frontiersin.org
Background Kawasaki disease (KD) has been considered as the most common required
pediatric cardiovascular diseases among the world. However, the molecular mechanisms of …

Neutrophil-to-lymphocyte ratio as a biomarker for predicting the intravenous immunoglobulin-resistant Kawasaki disease

G Wu, P Yue, F Ma, Y Zhang, X Zheng, Y Li - Medicine, 2020 - journals.lww.com
Background: In recent years, many studies focused on the association between the
neutrophil-to-lymphocyte ratio (NLR) and the risk of intravenous immunoglobulin (IVIG) …

Pharmacogenomics of intravenous immunoglobulin response in Kawasaki disease

S Shrestha, HW Wiener, H Kajimoto… - Frontiers in …, 2024 - frontiersin.org
Introduction Kawasaki disease (KD) is a diffuse vasculitis in children. Response to high dose
intravenous gamma globulin (IVIG), the primary treatment, varies according to genetic …

HMGB1 gene polymorphism is associated with coronary artery lesions and intravenous immunoglobulin resistance in Kawasaki disease

JG Ahn, Y Bae, D Shin, J Nam, KY Kim, DS Kim - Rheumatology, 2019 - academic.oup.com
Objectives Kawasaki disease (KD) is an acute systemic vasculitis of unknown aetiology that
affects infants and young children. Recent reports of elevated serum high mobility group box …

Kawasaki disease and clinical outcome disparities among black children

LA Padilla, JL Collins, AJ Idigo, Y Lau… - The Journal of …, 2021 - Elsevier
Objective To determine whether Black children with Kawasaki disease exhibit disparities in
prevalence, sequelae, and response to intravenous gamma globulin (IVIG) treatment. Study …