Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Pulmonary functional MRI: Detecting the structure–function pathologies that drive asthma symptoms and quality of life

HK Kooner, MJ McIntosh, V Desaigoudar… - …, 2022 - Wiley Online Library
Pulmonary functional MRI (PfMRI) using inhaled hyperpolarized, radiation‐free gases (such
as 3He and 129Xe) provides a way to directly visualize inhaled gas distribution and …

[HTML][HTML] CT mucus score and 129Xe MRI ventilation defects after 2.5 years' anti-IL-5Rα in eosinophilic asthma

MJ McIntosh, HK Kooner, RL Eddy, A Wilson… - Chest, 2023 - Elsevier
Background We previously showed in patients with poorly controlled eosinophilic asthma
that a single dose of benralizumab resulted in significantly improved Asthma Control …

Specific Ventilation in Severe Asthma Evaluated with Noncontrast Tidal Breathing 1H MRI

DPI Capaldi, NB Konyer, M Kjarsgaard… - Radiology …, 2023 - pubs.rsna.org
Purpose To determine if proton (1H) MRI–derived specific ventilation is responsive to
bronchodilator (BD) therapy and associated with clinical biomarkers of type 2 airway …

[HTML][HTML] 129Xe MRI ventilation defects in asthma: what is the upper limit of normal and minimal clinically important difference?

MJ McIntosh, A Biancaniello, HK Kooner, A Bhalla… - Academic …, 2023 - Elsevier
Rationale and Objectives The minimal clinically important difference (MCID) and upper limit
of normal (ULN) for MRI ventilation defect percent (VDP) were previously reported for …

Functional lung imaging using novel and emerging MRI techniques

CT Foo, D Langton, BR Thompson, F Thien - Frontiers in Medicine, 2023 - frontiersin.org
Respiratory diseases are leading causes of death and disability in the world. While early
diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools …

Efficacy and safety of moxibustion as a complementary and alternative therapy for asthma: A systematic review and meta-analysis

G Deng, X Feng, H Zhang, L Li, Q Cao, Y Fu… - International …, 2024 - Elsevier
Objective This systematic review of randomized controlled trials (RCTs) aimed to evaluate
the efficacy and safety of moxibustion as a complementary or alternative treatment for …

Assessment of pulmonary morphometry using hyperpolarized 129Xe diffusion‐weighted MRI with variable‐sampling‐ratio compressed sensing patterns

Q Zhou, H Li, Q Rao, M Zhang, X Zhao, L Shen… - Medical …, 2023 - Wiley Online Library
Abstract Background Hyperpolarized (HP) 129Xe multiple b‐values diffusion‐weighted
magnetic resonance imaging (DW‐MRI) has been widely used for quantifying pulmonary …

Imaging in asthma management

PJ Niedbalski, J Choi, CS Hall… - Seminars in Respiratory …, 2022 - thieme-connect.com
Asthma is a heterogeneous disease characterized by chronic airway inflammation that
affects more than 300 million people worldwide. Clinically, asthma has a widely variable …

New Frontiers in Asthma Chest Imaging

AM Matheson, J Johnstone, PJ Niedbalski… - Journal of Allergy and …, 2024 - Elsevier
Modern pulmonary imaging can reveal underlying pathological and pathophysiological
changes in the lungs of people with asthma, with important clinical implications. A multitude …