C-reactive protein and cancer—diagnostic and therapeutic insights

PC Hart, IM Rajab, M Alebraheem… - Frontiers in …, 2020 - frontiersin.org
Cancer disease describes any pathology involving uncontrolled cell growth. As cells
duplicate, they can remain localized in defined tissues, forming tumor masses and altering …

The predictive value of inflammation-related peripheral blood measurements in cancer staging and prognosis

JL Sylman, A Mitrugno, M Atallah, GW Tormoen… - Frontiers in …, 2018 - frontiersin.org
In this review, we discuss the interaction between cancer and markers of inflammation (such
as levels of inflammatory cells and proteins) in the circulation, and the potential benefits of …

A novel systemic inflammation response index (SIRI) for predicting the survival of patients with pancreatic cancer after chemotherapy

Q Qi, L Zhuang, Y Shen, Y Geng, S Yu, H Chen, L Liu… - Cancer, 2016 - Wiley Online Library
BACKGROUND Predicting survival is uniquely difficult in patients with pancreatic cancer
who receive chemotherapy. The authors developed a systemic inflammation response index …

The systemic-immune-inflammation index independently predicts survival and recurrence in resectable pancreatic cancer and its prognostic value depends on …

MH Aziz, K Sideras, NA Aziz, K Mauff, R Haen… - Annals of …, 2019 - journals.lww.com
Objective: Our aim was to determine the prognostic significance of the systemic-immune-
inflammation index (SIII) in patients with resectable pancreatic cancer, using cancer-specific …

Phytosome complex of curcumin as complementary therapy of advanced pancreatic cancer improves safety and efficacy of gemcitabine: Results of a prospective …

D Pastorelli, ASC Fabricio, P Giovanis… - Pharmacological …, 2018 - Elsevier
A large body of biomedical evidence indicates that activation of Nrf2 by curcumin increases
the nucleophilic tone and damps inflammation cumulatively supporting the malignant …

The role of neutrophil to lymphocyte ratio for the assessment of liver fibrosis and cirrhosis: a systematic review

Y Peng, Y Li, Y He, Q Wei, Q Xie, L Zhang… - Expert review of …, 2018 - Taylor & Francis
Introduction: Neutrophil to lymphocyte ratio (NLR) is widely used to assess inflammatory
diseases. We performed a systematic review to explore the prognostic role of NLR for the …

The predictive potential of the baseline C-reactive protein levels for the efficiency of immune checkpoint inhibitors in cancer patients: a systematic review and meta …

CL Han, GX Meng, ZN Ding, ZR Dong… - Frontiers in …, 2022 - frontiersin.org
Background The relationship between baseline C-reactive protein (CRP) level and the
prognosis of cancer patients receiving immune checkpoint inhibitor (ICI) treatment remains …

Combined C-reactive protein and novel inflammatory parameters as a predictor in cancer—what can we learn from the hematological experience?

Ø Bruserud, HH Aarstad, THA Tvedt - Cancers, 2020 - mdpi.com
The acute phase reaction is a systemic response to acute or chronic inflammation. The
serum level of C-reactive protein (CRP) is the only acute phase biomarker widely used in …

Preoperative neutrophil-lymphocyte and lymphocyte-monocyte ratios reflect immune cell population rearrangement in resectable pancreatic cancer

M Sierzega, M Lenart, M Rutkowska, M Surman… - Annals of surgical …, 2017 - Springer
Background Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and
lymphocyte-monocyte ratio (LMR) may serve as a simple index of the immune function. The …

Systemic immune-inflammation index and changes of neutrophil-lymphocyte ratio as prognostic biomarkers for patients with pancreatic cancer treated with immune …

J Shang, X Han, H Zha, H Tao, X Li, F Yuan… - Frontiers in …, 2021 - frontiersin.org
The efficacy of current treatment regimens for pancreatic cancer (PC) remains unsatisfactory.
In recent years, immune checkpoint blockade (ICB) therapy has shown promising anti-tumor …