Ultrafast and slow cholinergic transmission. Different involvement of acetylcholinesterase molecular forms

Y Dunant, V Gisiger - Molecules, 2017 - mdpi.com
Acetylcholine (ACh), an ubiquitous mediator substance broadly expressed in nature, acts as
neurotransmitter in cholinergic synapses, generating specific communications with different …

[HTML][HTML] Extricating hydrogeochemical evolution of geothermal fluids of an unexplored section in North-Eastern Himalayas, Arunachal geothermal province, India

A Dutta, RJ Singh, S Debnath, P Mishra, RK Gupta… - Solid Earth …, 2023 - Elsevier
The thermal springs of the study area are situated in North-eastern Arunachal Himalayas,
India along Subansiri and Siang River valleys with surface temperature ranging between 20 …

Association of soil selenium, strontium, and magnesium concentrations with Parkinson's disease mortality rates in the USA

H Sun - Environmental geochemistry and health, 2018 - Springer
Among the 41 soil elements analyzed from 4856 sites across the contiguous 48 states,
average Parkinson's disease (PD) mortality rates between 1999 and 2014 have the most …

The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells

KA Price, JL Hickey, Z Xiao, AG Wedd, SA James… - Chemical …, 2012 - pubs.rsc.org
Copper is an essential biometal involved in critical cell functions including respiration.
However, the mechanisms controlling its sub-cellular localization during health and disease …

Integrated multivariate analysis, hydrogeochemical modelling and speciation studies to reveal geogenic origins behind physical disabilities: a case study in Pure …

PK Singh, SK Singh, S Debnath, A Dutta - Journal of the Geological …, 2022 - Springer
The study aims to discuss elaborately about the origin of physical disabilities amongst the
locals of Pure village in Varanasi district, India through proper hydrogeochemical facies …

Na+/Ca2+ exchanger 2‐heterozygote knockout mice display decreased acetylcholine release and altered colonic motility in vivo

YT Azuma, K Nishiyama, S Kita… - …, 2012 - Wiley Online Library
Abstract Background The Na+/Ca2+ exchanger (NCX) is a plasma membrane transporter
involved in regulating intracellular Ca2+ concentrations. NCX is critical for Ca2+ regulation …

Activation of a TRP-like channel and intracellular Ca2+ dynamics during phospholipase-C-mediated cell death

AP Goncalves, JM Cordeiro, J Monteiro… - Journal of Cell …, 2014 - journals.biologists.com
The model organism Neurospora crassa undergoes programmed cell death when exposed
to staurosporine. Here, we show that staurosporine causes defined changes in cytosolic free …

Synaptic abnormalities of mice lacking toll-like receptor (TLR)-9

V Patel, AM Patel, JJ McArdle - Neuroscience, 2016 - Elsevier
Motor, sensory, and autonomic abnormalities are reported for toll-like receptor 9 (TLR9)
knock-out (KO) mice. However, a physiological role of TLR9 in the nervous system is largely …

Synaptotagmin 1 is required for vesicular Ca2+/H+‐antiport activity

JM Cordeiro, B Boda, PP Gonçalves… - Journal of …, 2013 - Wiley Online Library
Abstract A low‐affinity Ca2+/H+‐antiport was described in the membrane of mammalian
brain synaptic vesicles. Electrophysiological studies showed that this antiport contributes to …

Estimation of the mitochondrial calcium pool in rat brain synaptosomes using Rhod-2 AM fluorescent dye

SV Hrynevich, TV Waseem, SV Fedorovich - Biophysics, 2017 - Springer
The literature data on the role of synaptic mitochondria in the regulation of the cytosolic
calcium level are contradictory. In the present paper calcium storage by mitochondria in rat …