Diagnosis and treatment of keloids and hypertrophic scars—Japan scar workshop consensus document 2018

R Ogawa, S Akita, S Akaishi, N Aramaki-Hattori… - Burns & …, 2019 - academic.oup.com
There has been a long-standing need for guidelines on the diagnosis and treatment of
keloids and hypertrophic scars that are based on an understanding of the pathomechanisms …

[HTML][HTML] Keloids: a review of etiology, prevention, and treatment

U Betarbet, TW Blalock - The Journal of clinical and aesthetic …, 2020 - ncbi.nlm.nih.gov
Keloids are abnormal scars that cause significant emotional and physical distress in patients
when inadequately treated. Keloid formation is theorized to occur as a result of an …

[HTML][HTML] Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis–keloids and hypertrophic scars may be vascular disorders

R Ogawa, S Akaishi - Medical Hypotheses, 2016 - Elsevier
Keloids and hypertrophic scars are fibroproliferative disorders (FPDs) of the skin that result
from abnormal healing of injured or irritated skin. They can be called pathological or …

[HTML][HTML] The most current algorithms for the treatment and prevention of hypertrophic scars and keloids: a 2020 update of the algorithms published 10 years ago

R Ogawa - Plastic and reconstructive surgery, 2022 - journals.lww.com
Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Surgical excision and postoperative radiotherapy for keloids

R Ogawa, M Tosa, T Dohi, S Akaishi… - Scars, Burns & …, 2019 - journals.sagepub.com
Keloids can be treated in a number of ways, including by surgery. Multiple studies now show
that while surgical monotherapy associates with extremely high rates of recurrence (50 …

Optimizing surgical outcome of auricular keloid with a novel multimodal approach

YT Hung, SM Lin, IS Tzeng, CY Ng - Scientific Reports, 2022 - nature.com
Various treatments are available for auricular keloids, but none has an absolute advantage.
A practical and safe therapy to optimize the surgical outcome for auricular keloids is needed …

Adjuvant radiotherapy for keloids

W Dong, B Qiu, F Fan - Aesthetic plastic surgery, 2022 - Springer
Radiotherapy is one of the therapeutic methods for keloids, and the irradiation technique
has innovated from superficial X-ray to brachytherapy after decades of clinical practice. At …

[HTML][HTML] Radiation therapy for the adjunctive treatment of surgically excised keloids: a review

N Cheraghi, A Cognetta Jr… - The Journal of clinical and …, 2017 - ncbi.nlm.nih.gov
BACKGROUND: Radiotherapy has been used historically to treat a wide variety of
dermatologie conditions, including nonmelanoma skin cancers, lymphomas, and …

Histology and vascular architecture study of keloid tissue to outline the possible terminology of keloid skin flaps

Y Teng, Y Hao, H Liu, M Shan, Q Chen, K Song… - Aesthetic Plastic …, 2022 - Springer
Background Using the keloid “epidermis” to cover a wound is widely used during treatment
for keloids. Many flap terminologies have been used in literature. However, the definition of …

[HTML][HTML] Direct delivery of apatite nanoparticle-encapsulated siRNA targeting TIMP-1 for intractable abnormal scars

M Aoki, NM Matsumoto, T Dohi, H Kuwahawa… - … Therapy-Nucleic Acids, 2020 - cell.com
Hypertrophic scars (HSs) and keloids are histologically characterized by excessive
extracellular matrix (ECM) deposition. ECM deposition depends on the balance between …