An engineered TNFR1-selective human lymphotoxin-alpha mutant delivered by an oncolytic adenovirus for tumor immunotherapy

Y Cheng, Y Liu, D Xu, D Zhang, Y Yang, Y Miao… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Lymphotoxin α (LTα) is a soluble factor produced by activated lymphocytes which is
cytotoxic to tumor cells. Although a promising candidate in cancer therapy, the application of …

Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells

V Upadhyay, YX Fu - Cytokine & growth factor reviews, 2014 - Elsevier
The lymphotoxin (LT)-pathway is a unique constituent branch of the Tumor Necrosis
Superfamily (TNFSF). Use of LT is a critical mechanism by which fetal innate lymphoid cells …

Inflammatory pathway genes associated with inter-individual variability in the trajectories of morning and evening fatigue in patients receiving chemotherapy

F Wright, M Hammer, SM Paul, BE Aouizerat, KM Kober… - Cytokine, 2017 - Elsevier
Fatigue, a highly prevalent and distressing symptom during chemotherapy (CTX),
demonstrates diurnal and interindividual variability in severity. Little is known about the …

Innate lymphoid cells as novel regulators of obesity and its‐associated metabolic dysfunction

D Yang, W Yang, Z Tian, JC van Velkinburgh… - obesity …, 2016 - Wiley Online Library
The increased prevalence of obesity worldwide has been accompanied by increases in risk
and rates of obesity‐associated metabolic dysfunctions, such as insulin resistance. The …

Hepatitis B virus covalently closed circular DNA homeostasis is independent of the lymphotoxin pathway during chronic HBV infection

MA Meier, A Suslov, S Ketterer, MH Heim… - Journal of viral …, 2017 - Wiley Online Library
Current treatment options for patients with chronic hepatitis B virus (HBV) infection are not
curative as they are not effective in eliminating covalently closed circular DNA (ccc DNA) …

[PDF][PDF] 胆汁酸, 代谢手术与2 型糖尿病

张翔, 张光永, 刘少壮, 王琰珉… - 腹腔镜外科 …, 2014 - dzj-prod-1.oss-cn-shanghai.aliyuncs …
胆汁酸是胆汁中的主要成分, 在肝脏微粒体内由胆固醇转化合成, 通过胆道系统排泄进入肠道,
介导脂类, 脂溶性维生素等物质的吸收. 近年研究发现, 胆汁酸不仅是食物消化吸收中的重要物质 …

Влияние однонуклеотидных полиморфизмов генов TNF и LTA на клинические параметры и маркеры воспаления у пациентов с муковисцидозом

ГВ Шмарина, ДА Пухальская, АМ Букина… - Медицинская …, 2017 - elibrary.ru
Цель настоящей работы состояла в исследовании влияния аллельного полиморфизма
генов TNF (транзиция GA в промоторной области в позиции-308) и LTA (транзиция AG …

A Current Review on Gut Microbiota For Healthy Life.

B Harini, A Roy - Indian Journal of Forensic Medicine & …, 2020 - search.ebscohost.com
The human gastrointestinal tract is highly populated by a vast and diverse community of
different microbes. Every individual is provided with a unique gut microbiota which varies …

Study of a Germline Variant in Lymphotoxin Alpha (LTA) Gene in Colorectal Cancer

FCL Pinheiro - 2019 - repositorio.utad.pt
O cancro colorretal (CRC) representa a quarta causa de morte relacionada com o cancro no
mundo. Sendo causada por diversos fatores de risco como a dieta, história familiar …

TNF and LTA gene polymorphisms in cystic fibrosis patients: clinical parameters and inflammatory markers

GV Shmarina, DA Pukhalskaya, AM Bukina… - Medical …, 2017 - medgen-journal.ru
The aim of the study was to investigate clinical parameters and inflammatory markers in
cystic fibrosis patients (CF) with TNF and LTA gene polymorphisms: a G-to-A transition in …