Life expectancy of humans has increased continuously up to the present days, but their
health status (healthspan) was not enhanced by similar extent. To decrease enormous …

Globally, psychiatric disorders, such as anxiety disorder, bipolar disorder, schizophrenia,
depression, autism spectrum disorder, and attention-deficit/hyperactivity disorder (ADHD) …

Drug inefficiency in patients with refractory seizures renders epilepsy a life-threatening and
challenging brain disorder and stresses the need for accurate seizure detection and …

Electroencephalography (EEG) is one of the main pillars used for the diagnosis and study of
epilepsy, readily employed after a possible first seizure has occurred. The most established …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is mainly
characterized by cognitive deficits. Although many studies have been devoted to developing …

Seizure is paroxysmal abnormal electrical discharges in the cerebral cortex. Inflammatory
pathways and oxidative stress are involved in the pathophysiology of seizures. Stress can …

In present work, a series of novel structural hybrids of 1, 3, 4-oxadiazole and carbamothioate
was designed by chemical modification of 2-(4-isobutylphenyl) propanoic acid. Target …

KQT-like subfamily (KCNQ) channels are voltage-gated, noninactivating potassium ion
channels, and their down-regulation has been implicated in several hyperexcitability-related …

Ketone bodies are considered alternative fuels for the brain when glucose availability is
limited. To determine the neuroregenerative potential of D, L-sodium-beta-hydroxybutyrate …

The state of therapeutic ketosis can be achieved by using the ketogenic diet (KD) or
exogenous ketone supplementation. It was suggested previously that the adenosinergic …