Patient-specific inverse modeling of in vivo cardiovascular mechanics with medical image-derived kinematics as input data: concepts, methods, and applications

JH Bracamonte, SK Saunders, JS Wilson, UT Truong… - Applied Sciences, 2022 - mdpi.com
Inverse modeling approaches in cardiovascular medicine are a collection of methodologies
that can provide non-invasive patient-specific estimations of tissue properties, mechanical …

Diagnosis and treatment of right heart failure in pulmonary vascular diseases: a national heart, lung, and blood institute workshop

JA Leopold, SM Kawut, MA Aldred… - Circulation: Heart …, 2021 - Am Heart Assoc
Right ventricular dysfunction is a hallmark of advanced pulmonary vascular, lung
parenchymal, and left heart disease, yet the underlying mechanisms that govern (mal) …

Hemodynamic characteristics in a cerebral aneurysm model using non-Newtonian blood analogues

H Yi, Z Yang, M Johnson, L Bramlage, B Ludwig - Physics of Fluids, 2022 - pubs.aip.org
This study aims to develop an experimentally validated computational fluid dynamics (CFD)
model to estimate hemodynamic characteristics in cerebral aneurysms (CAs) using non …

The rheology of the carotid sinus: a path toward bioinspired intervention

A Iskander, C Bilgi, R Naftalovich… - … in Bioengineering and …, 2021 - frontiersin.org
The association between blood viscosity and pathological conditions involving a number of
organ systems is well known. However, how the body measures and maintains appropriate …

Assessment of turbulent blood flow and wall shear stress in aortic coarctation using image-based simulations

R Perinajová, JF Juffermans, JL Mercado… - Biomedical engineering …, 2021 - Springer
In this study, we analyzed turbulent flows through a phantom (a 180∘ bend with narrowing)
at peak systole and a patient-specific coarctation of the aorta (CoA), with a pulsating flow …

In vitro hemodynamic performance of a blood pump for self-powered venous assist in univentricular hearts

R Rasooli, H Holmstrom, KET Giljarhus, IW Jolma… - Scientific Reports, 2024 - nature.com
Univentricular heart anomalies represent a group of severe congenital heart defects
necessitating early surgical intervention in infancy. The Fontan procedure, the final stage of …

In silico evaluation of a self-powered venous ejector pump for Fontan patients

R Rasooli, KET Giljarhus, A Hiorth, IW Jolma… - Cardiovascular …, 2023 - Springer
Abstract Purpose The Fontan circulation carries a dismal prognosis in the long term due to
its peculiar physiology and lack of a subpulmonic ventricle. Although it is multifactorial …

Hemodynamic interplay of vorticity, viscous energy loss, and kinetic energy from 4D Flow MRI and link to cardiac function in healthy subjects and Fontan patients

VP Kamphuis, AAW Roest… - American Journal …, 2021 - journals.physiology.org
The purpose of this study was to directly assess (patho) physiology of intraventricular
hemodynamic interplay between four-dimensional flow cardiovascular magnetic resonance …

On the significance of blood flow shear-rate-dependency in modeling of Fontan hemodynamics

H Wei, AL Cheng, NM Pahlevan - European Journal of Mechanics-B/Fluids, 2020 - Elsevier
For univentricular heart patients, the Fontan operation creates a unique non-physiologic
circulation where the pulmonary arteries are directly supplied from the systemic venous …

[HTML][HTML] Numerical simulation of the cavopulmonary connection flow with conduit stenoses of varying configurations

M Timofeeva, C Lav, MMH Cheung, A Ooi - Computers in Biology and …, 2023 - Elsevier
The circulation in the total cavopulmonary connection (TCPC) is a low-energy system which
operation and efficiency are subjected to multiple factors. Some retrospective studies report …